MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 581304 | Name: Demethylchlordimeform

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Demethylchlordimeform is a biochemiacl.

Chemical Structure

Demethylchlordimeform
Demethylchlordimeform
CAS#21787-80-4

Theoretical Analysis

MedKoo Cat#: 581304

Name: Demethylchlordimeform

CAS#: 21787-80-4

Chemical Formula: C9H11ClN2

Exact Mass: 182.0611

Molecular Weight: 182.65

Elemental Analysis: C, 59.18; H, 6.07; Cl, 19.41; N, 15.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Demethylchlordimeform; Demethylchlorphenamidine;
IUPAC/Chemical Name
Formamidine, N-(4-chloro-o-tolyl)-N'-methyl-
InChi Key
MZCHBOYMVBQHQC-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H11ClN2/c1-7-5-8(10)3-4-9(7)12-6-11-2/h3-6H,1-2H3,(H,11,12)
SMILES Code
C/N=C/NC1=CC=C(Cl)C=C1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 182.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen X, Ohta H, Ozoe F, Miyazawa K, Huang J, Ozoe Y. Functional and pharmacological characterization of a beta-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Insect Biochem Mol Biol. 2010 Jun;40(6):476-86. doi: 10.1016/j.ibmb.2010.04.007. Epub 2010 Apr 22. PubMed PMID: 20417278. 2: Ohtani A, Arai Y, Ozoe F, Ohta H, Narusuye K, Huang J, Enomoto K, Kataoka H, Hirota A, Ozoe Y. Molecular cloning and heterologous expression of an alpha-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Insect Mol Biol. 2006 Dec;15(6):763-72. PubMed PMID: 17201769. 3: Vehovszky A, Hiripi L, Elliott CJ. Octopamine is the synaptic transmitter between identified neurons in the buccal feeding network of the pond snail lymnaea stagnalis. Brain Res. 2000 Jun 9;867(1-2):188-99. PubMed PMID: 10837813. 4: Hiripi L, Nagy L, Hollingworth RM. In vitro and in vivo effects of formamidines in locust (Locusta migratoria migratorioides). Acta Biol Hung. 1999;50(1-3):81-7. PubMed PMID: 10574431. 5: Park JH, Keeley LL. The effect of biogenic amines and their analogs on carbohydrate metabolism in the fat body of the cockroach Blaberus discoidalis. Gen Comp Endocrinol. 1998 Apr;110(1):88-95. PubMed PMID: 9514848. 6: Raffa RB, Orr N, Connelly CD, Hollingworth RM. XAMI and DCDM, agonists at cAMP-associated octopamine receptors in cockroach nerve cord, produce centrally mediated antinociception in mice. Brain Res. 1991 Sep 20;559(2):211-9. PubMed PMID: 1686573. 7: Costa LG, Olibet G, Murphy SD. Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. Toxicol Appl Pharmacol. 1988 Apr;93(2):319-28. PubMed PMID: 2833825. 8: Hsu WH, Smith BE, Hollingworth RM. The bradycardic and mydriatic effects of chlordimeform and its demethylated analogs in the rat: antagonism by idazoxan but not by prazosin. Life Sci. 1988;43(23):1897-904. PubMed PMID: 2849009. 9: Costa LG, Murphy SD. Interaction of the pesticide chlordimeform with adrenergic receptors in mouse brain: an in vitro study. Arch Toxicol. 1987 Feb;59(5):323-7. PubMed PMID: 3034195. 10: Duffield PH, Dougan DF, Wade DN, Duffield AM. Effect of chlordimeform and clonidine on the turnover of P-octopamine in rat hypothalamus and striatum. Life Sci. 1986 Apr 7;38(14):1271-80. PubMed PMID: 3083168. 11: Lafon-Cazal M, Bockaert J. Pharmacological characterization of octopamine-sensitive adenylate cyclase in the flight muscle of Locusta migratoria L. Eur J Pharmacol. 1985 Dec 10;119(1-2):53-9. PubMed PMID: 2867922. 12: Rieger JA, Allen LV Jr, Fisher RC. Extraction and analysis of chlordimeform and demethylchlordimeform from human tissue samples. Bull Environ Contam Toxicol. 1985 Sep;35(3):397-405. PubMed PMID: 4041652. 13: Hashemzadeh H, Hollingworth RM, Voliva A. Receptors for 3H-octopamine in the adult firefly light organ. Life Sci. 1985 Aug 5;37(5):433-40. PubMed PMID: 3927094. 14: Knowles CO, Johnson TL. Effect of formamidines on 5-hydroxytryptamine uptake and biogenic amine levels in rat platelets. Toxicology. 1984 May 14;31(2):91-8. PubMed PMID: 6740694. 15: Bittar R, Bittar EE, Ueno K. Stimulation by octopamine of the sodium efflux in barnacle muscle fibres. Comp Biochem Physiol C. 1984;79(1):227-9. PubMed PMID: 6209063. 16: Long TF, Murdock LL. Stimulation of blowfly feeding behavior by octopaminergic drugs. Proc Natl Acad Sci U S A. 1983 Jul;80(13):4159-63. PubMed PMID: 16593335; PubMed Central PMCID: PMC394220. 17: Gole JW, Orr GL, Downer RG. Interaction of formamidines with octopamine-sensitive adenylate cyclase receptor in the nerve cord of Periplaneta americana L. Life Sci. 1983 Jun 27;32(26):2939-47. PubMed PMID: 6306370. 18: Johnson TL, Knowles CO. Interaction of formamidines with the platelet 5-hydroxytryptamine uptake system. Gen Pharmacol. 1982;13(4):299-307. PubMed PMID: 7129070. 19: Nathanson JA, Hunnicutt EJ. N-demethylchlordimeform: a potent partial agonist of octopamine-sensitive adenylate cyclase. Mol Pharmacol. 1981 Jul;20(1):68-75. PubMed PMID: 6270539. 20: Robinson CP, Pento JT. The effects of U-40481, demethylchlordimeform, and formetanate on calcium flux in the isolated rabbit aorta. Res Commun Chem Pathol Pharmacol. 1980 May;28(2):215-28. PubMed PMID: 6771843.

View History

Epertinib hydrochloride

Epertinib hydrochloride

Featured