Synonym
Nitroscanate; CGA 23654; CGA-23654GS; 23654; Lopatol
IUPAC/Chemical Name
Benzene, 1-isothiocyanato-4-(4-nitrophenoxy)-
InChi Key
SVMGVZLUIWGYPH-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H8N2O3S/c16-15(17)11-3-7-13(8-4-11)18-12-5-1-10(2-6-12)14-9-19/h1-8H
SMILES Code
O=[N+](C1=CC=C(OC2=CC=C(N=C=S)C=C2)C=C1)[O-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
272.28
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: Juneja TR, Talukdar A, Gupta RL. Mutagenicity of sulfoscanate: a comparative study. Mutat Res. 2002 Jul 25;518(2):155-61. PubMed PMID: 12113767.
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9: Gupta RL, Kaur IP, Juneja TR. Genotoxicity of potential metabolites of nitroscanate--an antischistosomal drug. Mutat Res. 1995 Dec;335(3):235-43. PubMed PMID: 8524338.
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16: Tojo JL, Santamarina MT. Oral pharmacological treatments for parasitic diseases of rainbow trout Oncorhynchus mykiss. I: Hexamita salmonis. Dis Aquat Organ. 1998 May 14;33(1):51-6. PubMed PMID: 9653458.
17: Genchi C, Traldi G, Manfredi MT. Field trials of nitroscanate and mebendazole in dogs. Vet Rec. 1990 Jul 7;127(1):24. PubMed PMID: 2385917.
18: Godfrey C. Vomiting after anthelmintic. Vet Rec. 1979 Apr 7;104(14):328. PubMed PMID: 552700.
19: Jacobs DE. Control of Toxocara canis in puppies: a comparison of screening techniques and evaluation of a dosing programme. J Vet Pharmacol Ther. 1987 Mar;10(1):23-9. PubMed PMID: 3586119.
20: Hopkins TJ. Efficacy of a tablet containing pyrantel embonate, febantel and praziquantel against T canis in dogs. Vet Rec. 1991 Apr 6;128(14):331. PubMed PMID: 2063526.
