Synonym
Chlorthiamid; Chlorothiamide; DCBN; Prefix; Chlortiamid;
IUPAC/Chemical Name
2,6-Dichlor-thiobenzamid
InChi Key
KGKGSIUWJCAFPX-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H5Cl2NS/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)
SMILES Code
NC(C1=C(Cl)C=CC=C1Cl)=S
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
206.08
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Laatikainen T, Heinonen-Tanski H. Mycorrhizal growth in pure cultures in the presence of pesticides. Microbiol Res. 2002;157(2):127-37. PubMed PMID: 12002401.
2: Bruun L, Koch C, Pedersen B, Jakobsen MH, Aamand J. A quantitative enzyme-linked immunoassay for the detection of 2, 6-dichlorobenzamide (BAM), a degradation product of the herbicide dichlobenil. J Immunol Methods. 2000 Jun 23;240(1-2):133-42. PubMed PMID: 10854608.
3: Eriksson C, Brittebo EB. Effects of the herbicide chlorthiamid on the olfactory mucosa. Toxicol Lett. 1995 Apr;76(3):203-8. PubMed PMID: 7539165.
4: Eriksson C, Brandt I, Brittebo E. Tissue-binding and toxicity of compounds structurally related to the herbicide dichlobenil in the mouse olfactory mucosa. Food Chem Toxicol. 1992 Oct;30(10):871-7. PubMed PMID: 1427510.
5: Brittebo EB, Eriksson C, Feil V, Bakke J, Brandt I. Toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice. Fundam Appl Toxicol. 1991 Jul;17(1):92-102. PubMed PMID: 1916084.
6: Leach RW, Biddington NL, Verloop A, Nimmo WB. A side effect of chlorthiamid and dichlobenil herbicides. Ann Appl Biol. 1971 Jan;67(1):137-44. PubMed PMID: 5549686.
7: Brown VK, Chambers PL, Ferrigan LW, Stevenson DE, Williams DA. Toxicological studies with the herbicide 2,6-dichloro-thiobenzamide (chlorthiamid, "Prefix"). Arch Toxikol. 1967;23(1):42-51. PubMed PMID: 5588846.
