BAY-438 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
MedKoo Cat#: 563840
Name: BAY-438
CAS#: 1295505-76-8
Chemical Formula: C20H16F3IN4O4S
Exact Mass: 591.9889
Molecular Weight: 592.33
Elemental Analysis: C, 40.55; H, 2.72; F, 9.62; I, 21.42; N, 9.46; O, 10.80; S, 5.41
The following data is based on the product molecular weight 592.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
