MedKoo Cat#: 581271 | Name: DBO-83 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DBO-83 is a novel nicotinic acetylcholine receptor agonist. Structurally related to epibatidine. Has antinociceptive properties in rodents.

Chemical Structure

DBO-83 HCl
DBO-83 HCl
CAS#95211-53-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 581271

Name: DBO-83 HCl

CAS#: 95211-53-1 (HCl)

Chemical Formula: C10H15Cl3N4

Exact Mass: 0.0000

Molecular Weight: 297.61

Elemental Analysis: C, 40.36; H, 5.08; Cl, 35.73; N, 18.83

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Synonym
DBO-83; DBO83; DBO83; DBO-83 hydrochloride
IUPAC/Chemical Name
3,8-Diazabicyclo(3.2.1)octane, 3-(6-chloro-3-pyridazinyl)-, dihydrochloride
InChi Key
FMBGHZXNKMHVDT-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13ClN4.2ClH/c11-9-3-4-10(14-13-9)15-5-7-1-2-8(6-15)12-7;;/h3-4,7-8,12H,1-2,5-6H2;2*1H
SMILES Code
ClC1=NN=C(N2CC(N3)CCC3C2)C=C1.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 297.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Decker MW, Meyer MD, Sullivan JP. The therapeutic potential of nicotinic acetylcholine receptor agonists for pain control. Expert Opin Investig Drugs. 2001 Oct;10(10):1819-30. Review. PubMed PMID: 11772288. 2. Lloyd, G.K. et al., Neuronal nicotinic acetylcholine receptors as novel drug targets. J. Pharmacol. Exp. Ther. 292, 461, (2000) Ghelardini, C., Antinociceptive profile of the new nicotinic agonist DBO-83. Drug Dev. Res. 40, 251, (1997)