CCTA-1523 | CAS#1616271-41-0| ABCG2 inhibitor

MedKoo Cat#: 563818 | Name: CCTA-1523

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CCTA-1523 is an inhibitor of the efflux function of ABCG2. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells, both in vitro and in vivo.

Chemical Structure

CCTA-1523

CAS#1616271-41-0

Theoretical Analysis

MedKoo Cat#: 563818

Name: CCTA-1523

CAS#: 1616271-41-0

Chemical Formula: C16H15Cl2NO3

Exact Mass: 339.0429

Molecular Weight: 340.20

Elemental Analysis: C, 56.49; H, 4.44; Cl, 20.84; N, 4.12; O, 14.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CCTA-1523; CCTA1523; CCTA 1523

IUPAC/Chemical Name

2,2-Dichloro-N-(3',4'-dimethoxy-[1,1'-biphenyl]-3-yl) acetamide

InChi Key

KVFQJGFFQSVTND-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H15Cl2NO3/c1-21-13-7-6-11(9-14(13)22-2)10-4-3-5-12(8-10)19-16(20)15(17)18/h3-9,15H,1-2H3,(H,19,20)

SMILES Code

O=C(NC1=CC(C2=CC=C(OC)C(OC)=C2)=CC=C1)C(Cl)Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Patel A, Li TW, Anreddy N, Wang DS, Sodani K, Gadhia S, Kathawala R, Yang DH, Cheng C, Chen ZS. Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport. Pharmacol Res. 2017 Jul;121:184-193. doi: 10.1016/j.phrs.2017.04.025. Epub 2017 Apr 26. PubMed PMID: 28455266.