MedKoo Cat#: 584541 | Name: 4-Fluoro-thalidomide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

4-Fluoro-thalidomide, also known as TC E3 5032, is a precursor to Pomalidomide-based PROTACs.

Chemical Structure

4-Fluoro-thalidomide
4-Fluoro-thalidomide
CAS#835616-60-9

Theoretical Analysis

MedKoo Cat#: 584541

Name: 4-Fluoro-thalidomide

CAS#: 835616-60-9

Chemical Formula: C13H9FN2O4

Exact Mass: 276.0546

Molecular Weight: 276.22

Elemental Analysis: C, 56.53; H, 3.28; F, 6.88; N, 10.14; O, 23.17

Price and Availability

Size Price Availability Quantity
100mg USD 250.00 2 Weeks
250mg USD 350.00 2 Weeks
1g USD 550.00 2 Weeks
5g USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
TC E3 5032; TC E35032; TC E3-5032; TCE3 5032; TCE35032; TCE3-5032; 4-Fluoro-thalidomide;
IUPAC/Chemical Name
2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
InChi Key
CRAUTELYXAAAPW-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
SMILES Code
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 276.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID: 28418626