MedKoo Cat#: 584534 | Name: Kuanoniamine A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kuanoniamine A is a potent growth inhibitor human tumor and a non-tumor cell lines

Chemical Structure

Kuanoniamine A
Kuanoniamine A
CAS#133401-10-2

Theoretical Analysis

MedKoo Cat#: 584534

Name: Kuanoniamine A

CAS#: 133401-10-2

Chemical Formula: C16H7N3OS

Exact Mass: 289.0310

Molecular Weight: 289.31

Elemental Analysis: C, 66.43; H, 2.44; N, 14.52; O, 5.53; S, 11.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Kuanoniamine A
IUPAC/Chemical Name
9H-Pyrido(4,3,2-mn)thiazolo(4,5-b)acridin-9-one
InChi Key
SABDUJMZZVLRAS-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H7N3OS/c20-15-13-11-9(8-3-1-2-4-10(8)19-13)5-6-17-12(11)14-16(15)21-7-18-14/h1-7H
SMILES Code
O=C1C(SC=N2)=C2C3=NC=CC4=C5C=CC=CC5=NC1=C43
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 289.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kijjoa A, Wattanadilok R, Campos N, Nascimento MS, Pinto M, Herz W. Anticancer activity evaluation of kuanoniamines A and C isolated from the marine sponge Oceanapia sagittaria, collected from the Gulf of Thailand. Mar Drugs. 2007 Apr 17;5(2):6-22. PubMed PMID: 18463725; PubMed Central PMCID: PMC2365692. 2: Utkina NK. Sagitol D, a New Thiazole Containing Pyridoacridine Alkaloid from a Vietnamese Ascidian. Nat Prod Commun. 2015 Sep;10(9):1547-8. PubMed PMID: 26594755. 3: Tapia RA, Prieto Y, Pautet F, Walchshofer N, Fillion H, Fenet B, Sarciron ME. Synthesis and antiprotozoal evaluation of benzothiazolopyrroloquinoxalinones, analogues of kuanoniamine A. Bioorg Med Chem. 2003 Aug 5;11(16):3407-12. PubMed PMID: 12878135.