MedKoo Cat#: 584533 | Name: KT 1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs.

Chemical Structure

KT 1
KT 1
CAS#47487-05-8

Theoretical Analysis

MedKoo Cat#: 584533

Name: KT 1

CAS#: 47487-05-8

Chemical Formula: C16H22N4O6

Exact Mass: 366.1539

Molecular Weight: 366.37

Elemental Analysis: C, 52.45; H, 6.05; N, 15.29; O, 26.20

Price and Availability

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50mg USD 315.00
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Related CAS #
No Data
Synonym
KT 1; KT1; KT-1
IUPAC/Chemical Name
1-Pentanol, 5-((6,7,8-trimethoxy-4-quinazolinyl)amino)-, nitrate (ester)
InChi Key
XEMQGFBCRICHHG-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H22N4O6/c1-23-12-9-11-13(15(25-3)14(12)24-2)18-10-19-16(11)17-7-5-4-6-8-26-20(21)22/h9-10H,4-8H2,1-3H3,(H,17,18,19)
SMILES Code
COC1=C(OC)C(OC)=CC2=C(NCCCCCO[N+]([O-])=O)N=CN=C12
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Biological target:
TBD
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 366.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Miyamoto Y, Noguchi K, Nakasone J, Sakanashi M. Pharmacological properties of 5-[(6,7,8-trimethoxy-4-quinazolinyl) amino]-1-pentanyl nitrate maleate in cardiovascular system. Arzneimittelforschung. 1991 Dec;41(12):1216-21. PubMed PMID: 1815519. 2: Shakya S, Munshi P. Error analysis of tomographic reconstructions in the absence of projection data. Philos Trans A Math Phys Eng Sci. 2015 Jun 13;373(2043). pii: 20140394. doi: 10.1098/rsta.2014.0394. PubMed PMID: 25939629.