MedKoo Cat#: 109523 | Name: Inulicin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Inulicin is a sesquiterpene lactone isolated from Inula species, particularly Inula helenium, and is known for its bioactive properties, including anti-inflammatory and antimicrobial effects. Its mechanism of action is thought to involve the inhibition of pro-inflammatory mediators such as nitric oxide (NO) and cytokines, likely through suppression of NF-κB signaling pathways. As a member of the eudesmanolide class of sesquiterpenes, inulicin may also interact with cellular thiol groups, contributing to its bioactivity via alkylation of protein cysteine residues.

Chemical Structure

Inulicin
Inulicin
CAS#33627-41-7

Theoretical Analysis

MedKoo Cat#: 109523

Name: Inulicin

CAS#: 33627-41-7

Chemical Formula: C17H24O5

Exact Mass: 308.1600

Molecular Weight: 308.37

Elemental Analysis: C, 66.21; H, 7.85; O, 25.94

Price and Availability

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1mg USD 385.00 2 Weeks
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Synonym
IUPAC/Chemical Name
3-[(3aS,4R,5R,8aR)-4-Hydroxy-5,7-dimethyl-3-methylidene-2-oxo-4,5,8,8a-tetrahydro-3aH-cyclohepta[b]furan-6-yl]propyl acetate
InChi Key
QKVABRCMWRXFAF-HMTTWLPMSA-N
InChi Code
InChI=1S/C17H24O5/c1-9-8-14-15(11(3)17(20)22-14)16(19)10(2)13(9)6-5-7-21-12(4)18/h10,14-16,19H,3,5-8H2,1-2,4H3/t10-,14-,15-,16-/m1/s1
SMILES Code
CC(OCCCC1=C(C)C[C@@]([C@@]([C@H](O)[C@@H]1C)([H])C2=C)([H])OC2=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 308.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li JJ, Wen JK, Han M. [Inulicin inhibits activation and expression of vascular remodeling enzymes induced by de-endothelium]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2008 May;24(2):156-60. Chinese. PubMed PMID: 21141515. 2: Zhao J, Wen J, Han M. [Determination of acetylbritannilactone in inulicin and rat plasma by micellar electrokinetic capillary chromatography with on-line sweeping concentration technique]. Se Pu. 2006 Sep;24(5):508-12. Chinese. PubMed PMID: 17165550. 3: Belova LF, Baginskaia AI, Trumpe TE, Sokolov SIa, Rybalko KS. [Pharmacological properties of inulicin, a sesquiterpene lactone from Japanese inula]. Farmakol Toksikol. 1981 Jul-Aug;44(4):463-7. Russian. PubMed PMID: 7286207.