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MedKoo Cat#: 593078 | Name: Indoxacarb

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Indoxacarb is an Oxadiazine insecticide.

Chemical Structure

Indoxacarb
Indoxacarb
CAS#173584-44-6

Theoretical Analysis

MedKoo Cat#: 593078

Name: Indoxacarb

CAS#: 173584-44-6

Chemical Formula: C22H17ClF3N3O7

Exact Mass: 527.0707

Molecular Weight: 527.84

Elemental Analysis: C, 50.06; H, 3.25; Cl, 6.72; F, 10.80; N, 7.96; O, 21.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Indoxacarb
IUPAC/Chemical Name
Indeno(1,2-e)(1,3,4)oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-(((methoxycarbonyl)(4-(trifluoromethoxy)phenyl)amino)carbonyl)-, methyl ester, (4aS)-
InChi Key
VBCVPMMZEGZULK-NRFANRHFSA-N
InChi Code
InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3/t21-/m0/s1
SMILES Code
O=C([C@]1(CC2=C3C=CC(Cl)=C2)C3=NN(C(N(C(OC)=O)C4=CC=C(OC(F)(F)F)C=C4)=O)CO1)OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 527.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Alister C, Araya M, Becerra K, Volosky C, Saavedra J, Kogan M. Industrial prune processing and its effect on pesticide residue concentrations. Food Chem. 2018 Dec 1;268:264-270. doi: 10.1016/j.foodchem.2018.06.090. Epub 2018 Jun 19. PubMed PMID: 30064756. 2: Shi L, Gui T, Zhao S, Xu J, Wang F, Sui C, Zhang Y, Hu D. Degradation and residues of indoxacarb enantiomers in rice plants, rice hulls and brown rice using enriched S-indoxacarb formulation and enantiopure formulation. Biomed Chromatogr. 2018 May 30:e4301. doi: 10.1002/bmc.4301. [Epub ahead of print] PubMed PMID: 29847698. 3: Koppenhöfer AM, Kostromytska OS, Wu S. Pyrethroid-Resistance Level Affects Performance of Larvicides and Adulticides From Different Insecticide Classes in Populations of Listronotus maculicollis (Coleoptera: Curculionidae). J Econ Entomol. 2018 May 25. doi: 10.1093/jee/toy142. [Epub ahead of print] PubMed PMID: 29800225. 4: Cui L, Wang Q, Qi H, Wang Q, Yuan H, Rui C. Resistance selection of indoxacarb in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae): cross-resistance, biochemical mechanisms and associated fitness costs. Pest Manag Sci. 2018 Apr 29. doi: 10.1002/ps.5056. [Epub ahead of print] PubMed PMID: 29707889. 5: Li B, Lin J, Pang X, Li H, Li X, Liu F, Mu W. Binary mixtures of alcohol ethoxylates, nonylphenol ethoxylates and pesticides exhibit comparative bioactivity against three pests and toxicological risks to aquatic organisms. Chemosphere. 2018 Aug;204:44-50. doi: 10.1016/j.chemosphere.2018.04.034. Epub 2018 Apr 7. PubMed PMID: 29649663. 6: Wang X, Xiang X, Yu H, Liu S, Yin Y, Cui P, Wu Y, Yang J, Jiang C, Yang Q. Monitoring and biochemical characterization of beta-cypermethrin resistance in Spodoptera exigua (Lepidoptera: Noctuidae) in Sichuan Province, China. Pestic Biochem Physiol. 2018 Apr;146:71-79. doi: 10.1016/j.pestbp.2018.02.008. Epub 2018 Mar 2. PubMed PMID: 29626995. 7: Qin C, Wang CH, Wang YY, Sun SQ, Wang HH, Xue CB. Resistance to Diamide Insecticides in Plutella xylostella (Lepidoptera: Plutellidae): Comparison Between Lab-Selected Strains and Field-Collected Populations. J Econ Entomol. 2018 Apr 2;111(2):853-859. doi: 10.1093/jee/toy043. PubMed PMID: 29529288. 8: Gao Y, Kim K, Kwon DH, Jeong IH, Clark JM, Lee SH. Transcriptome-based identification and characterization of genes commonly responding to five different insecticides in the diamondback moth, Plutella xylostella. Pestic Biochem Physiol. 2018 Jan;144:1-9. doi: 10.1016/j.pestbp.2017.11.007. Epub 2017 Nov 22. PubMed PMID: 29463402. 9: Su T, Thieme J, Ocegueda C, Ball M, Cheng ML. Resistance to Lysinibacillus sphaericus and Other Commonly Used Pesticides in Culex pipiens (Diptera: Culicidae) from Chico, California. J Med Entomol. 2018 Feb 28;55(2):423-428. doi: 10.1093/jme/tjx235. PubMed PMID: 29272497. 10: Kostromytska OS, Wu S, Koppenhöfer AM. Cross-resistance Patterns to Insecticides of Several Chemical Classes Among Listronotus maculicollis (Coleoptera: Curculionidae) Populations With Different Levels of Resistance to Pyrethroids. J Econ Entomol. 2018 Feb 9;111(1):391-398. doi: 10.1093/jee/tox345. PubMed PMID: 29272414. 11: Li B, Li H, Pang X, Cui K, Lin J, Liu F, Mu W. Quaternary ammonium cationic surfactants increase bioactivity of indoxacarb on pests and toxicological risk to Daphnia magna. Ecotoxicol Environ Saf. 2018 Mar;149:190-196. doi: 10.1016/j.ecoenv.2017.11.038. Epub 2017 Nov 23. PubMed PMID: 29175345. 12: Bosch D, Rodríguez MA, Avilla J. Monitoring resistance of Cydia pomonella (L.) Spanish field populations to new chemical insecticides and the mechanisms involved. Pest Manag Sci. 2018 Apr;74(4):933-943. doi: 10.1002/ps.4791. Epub 2018 Jan 5. PubMed PMID: 29148167. 13: Ramos RS, de Araújo VCR, Pereira RR, Martins JC, Queiroz OS, Silva RS, Picanço MC. Investigation of the lethal and behavioral effects of commercial insecticides on the parasitoid wasp Copidosoma truncatellum. Chemosphere. 2018 Jan;191:770-778. doi: 10.1016/j.chemosphere.2017.10.113. Epub 2017 Nov 1. PubMed PMID: 29080538. 14: Smith LB, Kasai S, Scott JG. Voltage-sensitive sodium channel mutations S989P + V1016G in Aedes aegypti confer variable resistance to pyrethroids, DDT and oxadiazines. Pest Manag Sci. 2018 Mar;74(3):737-745. doi: 10.1002/ps.4771. Epub 2017 Dec 8. PubMed PMID: 29064635; PubMed Central PMCID: PMC5814875. 15: Li X, Shi H, Gao X, Liang P. Characterization of UDP-glucuronosyltransferase genes and their possible roles in multi-insecticide resistance in Plutella xylostella (L.). Pest Manag Sci. 2018 Mar;74(3):695-704. doi: 10.1002/ps.4765. Epub 2017 Nov 28. PubMed PMID: 29027758. 16: Demirci Ö, Güven K, Asma D, Öğüt S, Uğurlu P. Effects of endosulfan, thiamethoxam, and indoxacarb in combination with atrazine on multi-biomarkers in Gammarus kischineffensis. Ecotoxicol Environ Saf. 2018 Jan;147:749-758. doi: 10.1016/j.ecoenv.2017.09.038. Epub 2017 Sep 21. PubMed PMID: 28942278. 17: Hu B, Zhang SH, Ren MM, Tian XR, Wei Q, Mburu DK, Su JY. The expression of Spodoptera exigua P450 and UGT genes: tissue specificity and response to insecticides. Insect Sci. 2017 Sep 7. doi: 10.1111/1744-7917.12538. [Epub ahead of print] PubMed PMID: 28881445. 18: Saddiq B, Ejaz M, Shad SA, Aslam M. Assessing the combined toxicity of conventional and newer insecticides on the cotton mealybug Phenacoccus solenopsis. Ecotoxicology. 2017 Nov;26(9):1240-1249. doi: 10.1007/s10646-017-1849-5. Epub 2017 Sep 1. PubMed PMID: 28865048. 19: Ghelichpour M, Taheri Mirghaed A, Mirzargar SS, Joshaghani H, Ebrahimzadeh Mousavi H. Modification of saltwater stress response in Cyprinus carpio (Linnaeus, 1758) pre-exposed to pesticide indoxacarb. Ecotoxicol Environ Saf. 2018 Jan;147:139-143. doi: 10.1016/j.ecoenv.2017.08.029. Epub 2017 Sep 14. PubMed PMID: 28841529. 20: Silva RS, Arcanjo LP, Soares JRS, Ferreira DO, Serrão JE, Martins JC, Costa ÁH, Picanço MC. Insecticide toxicity to the borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae): developmental and egg-laying effects. Neotrop Entomol. 2018 Apr;47(2):318-325. doi: 10.1007/s13744-017-0553-8. Epub 2017 Aug 18. PubMed PMID: 28822099.

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