KM 1146 | CAS#82697-73-2 | anti-ulcer

MedKoo Cat#: 584515 | Name: KM 1146

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KM 1146 has gastric anti-ulcer and cytoprotective properties in rat experimental ulcers.

Chemical Structure

KM 1146

CAS#82697-73-2

Theoretical Analysis

MedKoo Cat#: 584515

Name: KM 1146

CAS#: 82697-73-2

Chemical Formula: C12H15NO3S

Exact Mass: 253.0773

Molecular Weight: 253.32

Elemental Analysis: C, 56.90; H, 5.97; N, 5.53; O, 18.95; S, 12.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KM 1146; KM-1146; KM1146; Mezolidon

IUPAC/Chemical Name

4-Thiazolidinone, 2-(3,4-dimethoxyphenyl)-5-methyl-

InChi Key

AUPNGGXXLZJAHC-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H15NO3S/c1-7-11(14)13-12(17-7)8-4-5-9(15-2)10(6-8)16-3/h4-7,12H,1-3H3,(H,13,14)

SMILES Code

O=C1NC(C2=CC=C(OC)C(OC)=C2)SC1C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 253.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Matsuo Y, Kuwayama H, Itoh H, Seki A, Fukuda S, Kawasaki T, Hotta T, Ohsaka Y, Komatsu K. Gastric anti-ulcer and cytoprotective properties of 2-(3,4-dimethoxyphenyl)-5-methyl-thiazolidine-4-one in rat experimental ulcers. Arzneimittelforschung. 1986 Aug;36(8):1236-40. PubMed PMID: 3778561. 2: Ashida Y, Murakami M, Mizuno M, Saita H, Miyake T. [Anti-ulcer mechanism of mezolidon on water-immersion stress induced gastric ulcers in rats]. Nihon Yakurigaku Zasshi. 1988 Mar;91(3):121-7. Japanese. PubMed PMID: 3371796.