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MedKoo Cat#: 461920 | Name: Schisantherin D

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Schisantherin D is a lignan isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.

Chemical Structure

Schisantherin D
Schisantherin D
CAS#64917-82-4

Theoretical Analysis

MedKoo Cat#: 461920

Name: Schisantherin D

CAS#: 64917-82-4

Chemical Formula: C29H28O9

Exact Mass: 520.1733

Molecular Weight: 520.53

Elemental Analysis: C, 66.92; H, 5.42; O, 27.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Schisantherin D; Schisantherin-D;
IUPAC/Chemical Name
A name could not be generated for this structure.
InChi Key
PGEJVRVFUGSAJF-SSEZWIOCSA-N
InChi Code
InChI=1S/C29H28O9/c1-15-10-17-11-19-23(36-13-34-19)25(32-3)21(17)22-18(12-20-24(26(22)33-4)37-14-35-20)27(29(15,2)31)38-28(30)16-8-6-5-7-9-16/h5-9,11-12,15,27,31H,10,13-14H2,1-4H3/t15-,27-,29-/m0/s1
SMILES Code
COc1c2c([C@@H]([C@@](C)(O)[C@@H](C)Cc3c2c(OC)c(OCO4)c4c3)OC(c5ccccc5)=O)cc6c1OCO6
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 520.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Liu CS, Fang SD, Huang MF, Kao YL, Hsu JS. Studies on the active principles of Schisandra sphenanthera Rehd. et Wils. The structures of schisantherin A, B, C, D, E, and the related compounds. Sci Sin. 1978 Jul-Aug;21(4):483-502. PubMed PMID: 233922. 2: Liu H, Zhang J, Li X, Qi Y, Peng Y, Zhang B, Xiao P. Chemical analysis of twelve lignans in the fruit of Schisandra sphenanthera by HPLC-PAD-MS. Phytomedicine. 2012 Oct 15;19(13):1234-41. doi: 10.1016/j.phymed.2012.07.017. Epub 2012 Aug 18. PubMed PMID: 22906629. 3: Li YF, Jiang Y, Huang JF, Yang GZ. Four new lignans from Schisandra sphenanthera. J Asian Nat Prod Res. 2013 Sep;15(9):934-40. doi: 10.1080/10286020.2013.824428. Epub 2013 Aug 14. PubMed PMID: 23945017. 4: Li W, Song YG, Liu KY, Yang LJ, Liu YL, Su D, Feng YL. [Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MS~E combining with metabonomics]. Yao Xue Xue Bao. 2016 Sep;51(9):1445-50. Chinese. PubMed PMID: 29924538. 5: Liu H, Li X, Zhang J, Zhu Y, Qi Y, Peng Y, Zhang B, Xiao P. [Chemical constituents of petroleum ether extract of fruits of Schisandra sphenanthera]. Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(11):1597-601. Chinese. PubMed PMID: 22993989. 6: Sun R, Song HC, Wang CR, Shen KZ, Xu YB, Gao YX, Chen YG, Dong JY. Compounds from Kadsura angustifolia with anti-HIV activity. Bioorg Med Chem Lett. 2011 Feb 1;21(3):961-5. doi: 10.1016/j.bmcl.2010.12.055. Epub 2010 Dec 21. PubMed PMID: 21232955. 7: Chen DF, Zhang SX, Kozuka M, Sun QZ, Feng J, Wang Q, Mukainaka T, Nobukuni Y, Tokuda H, Nishino H, Wang HK, Morris-Natschke SL, Lee KH. Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation. J Nat Prod. 2002 Sep;65(9):1242-5. PubMed PMID: 12350139. 8: Chen DF, Zhang SX, Chen K, Zhou BN, Wang P, Cosentino LM, Lee KH. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8. PubMed PMID: 8946749. 9: Chen DF, Zhang SX, Xie L, Xie JX, Chen K, Kashiwada Y, Zhou BN, Wang P, Cosentino LM, Lee KH. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23. PubMed PMID: 9313872. 10: Xiao WL, Huang SX, Wang RR, Zhong JL, Gao XM, He F, Pu JX, Lu Y, Zheng YT, Zheng QT, Sun HD. Nortriterpenoids and lignans from Schisandra sphenanthera. Phytochemistry. 2008 Nov;69(16):2862-6. doi: 10.1016/j.phytochem.2008.09.010. Epub 2008 Oct 23. PubMed PMID: 18951592.