MedKoo Cat#: 592987 | Name: Methoxyphenamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methoxyphenamine inhibits basal and histamine-induced nasal congestion in anaesthetized rats.

Chemical Structure

Methoxyphenamine
Methoxyphenamine
CAS#93-30-1

Theoretical Analysis

MedKoo Cat#: 592987

Name: Methoxyphenamine

CAS#: 93-30-1

Chemical Formula: C11H17NO

Exact Mass: 179.1310

Molecular Weight: 179.26

Elemental Analysis: C, 73.70; H, 9.56; N, 7.81; O, 8.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Methoxyphenamine
IUPAC/Chemical Name
Phenethylamine, 2-methoxy-N,alpha-dimethyl-
InChi Key
OEHAYUOVELTAPG-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
SMILES Code
CC(NC)CC1=CC=CC=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 179.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: He Y, Lou X, Jin Z, Yu L, Deng L, Wan H. Mahuang decoction mitigates airway inflammation and regulates IL-21/STAT3 signaling pathway in rat asthma model. J Ethnopharmacol. 2018 Oct 5;224:373-380. doi: 10.1016/j.jep.2018.06.011. Epub 2018 Jun 12. PubMed PMID: 29906536. 2: Liang Y, Wang J, Fei F, Sun H, Liu T, Li Q, Zhao X, Zheng X. Binding kinetics of five drugs to beta2-adrenoceptor using peak profiling method and nonlinear chromatography. J Chromatogr A. 2018 Feb 23;1538:17-24. doi: 10.1016/j.chroma.2018.01.027. Epub 2018 Jan 12. PubMed PMID: 29373124. 3: Yu L, Xu X, Hang J, Cheng K, Jin X, Chen Q, Lv H, Qiu Z. Efficacy of sequential three-step empirical therapy for chronic cough. Ther Adv Respir Dis. 2017 Jun;11(6):225-232. doi: 10.1177/1753465817711187. PubMed PMID: 28597805; PubMed Central PMCID: PMC5933649. 4: Kim J, Choi K, Chung DS. In-line coupling of single-drop microextraction with capillary electrophoresis-mass spectrometry. Anal Bioanal Chem. 2015 Nov;407(29):8745-52. doi: 10.1007/s00216-015-9028-0. Epub 2015 Sep 24. PubMed PMID: 26403239. 5: Li Q, Wang J, Zheng YY, Yang L, Zhang Y, Bian L, Zheng J, Li Z, Zhao X, Zhang Y. Comparison of zonal elution and nonlinear chromatography in determination of the interaction between seven drugs and immobilised β(2)-adrenoceptor. J Chromatogr A. 2015 Jul 3;1401:75-83. doi: 10.1016/j.chroma.2015.05.012. Epub 2015 May 14. PubMed PMID: 26002106. 6: Kamata T, Shima N, Sasaki K, Matsuta S, Takei S, Katagi M, Miki A, Zaitsu K, Nakanishi T, Sato T, Suzuki K, Tsuchihashi H. Time-course mass spectrometry imaging for depicting drug incorporation into hair. Anal Chem. 2015 Jun 2;87(11):5476-81. doi: 10.1021/acs.analchem.5b00971. Epub 2015 May 6. PubMed PMID: 25919888. 7: Lebedeva MV, Prokhorova AF, Shapovalova EN, Shpigun OA. Clarithromycin as a chiral selector for enantioseparation of basic compounds in nonaqueous capillary electrophoresis. Electrophoresis. 2014 Oct;35(19):2759-64. doi: 10.1002/elps.201400135. Epub 2014 Aug 19. PubMed PMID: 25100556. 8: Zhao X, Li Q, Chen J, Xiao C, Bian L, Zheng J, Zheng X, Li Z, Zhang Y. Exploring drug-protein interactions using the relationship between injection volume and capacity factor. J Chromatogr A. 2014 Apr 25;1339:137-44. doi: 10.1016/j.chroma.2014.03.017. Epub 2014 Mar 12. PubMed PMID: 24666938. 9: Zhao X, Li Q, Xiao C, Zhang Y, Bian L, Zheng J, Zheng X, Li Z, Zhang Y, Fan T. Oriented immobilisation of histidine-tagged protein and its application in exploring interactions between ligands and proteins. Anal Bioanal Chem. 2014 May;406(12):2975-85. doi: 10.1007/s00216-014-7723-x. Epub 2014 Mar 15. PubMed PMID: 24633512. 10: Zhao XF, Huang JJ, Li Q, Wei LS, Zheng JB, Zheng XH, Li ZJ, Zhang YY. Revealing binding interaction between seven drugs and immobilized β2-adrenoceptor by high-performance affinity chromatography using frontal analysis. J Mol Recognit. 2013 May;26(5):252-7. doi: 10.1002/jmr.2271. PubMed PMID: 23526777. 11: Domínguez-Romero JC, García-Reyes JF, Martínez-Romero R, Berton P, Martínez-Lara E, Del Moral-Leal ML, Molina-Díaz A. Combined data mining strategy for the systematic identification of sport drug metabolites in urine by liquid chromatography time-of-flight mass spectrometry. Anal Chim Acta. 2013 Jan 25;761:1-10. doi: 10.1016/j.aca.2012.11.049. Epub 2012 Dec 5. PubMed PMID: 23312308. 12: Wei W, Yu L, Wang Y, Li X, Qiu Z, Wang L, Liu B, Liang S, Lü H, Qiu Z. Efficacy and safety of modified sequential three-step empirical therapy for chronic cough. Respirology. 2010 Jul;15(5):830-6. doi: 10.1111/j.1440-1843.2010.01785.x. Epub 2010 Jun 9. PubMed PMID: 20546197. 13: Moawad M, Khoo CS, Lee S, Hennell JR. Simultaneous determination of eight sympathomimetic amines in urine by gas chromatography/mass spectrometry. J AOAC Int. 2010 Jan-Feb;93(1):116-22. PubMed PMID: 20334173. 14: Thevis M, Sigmund G, Geyer H, Schänzer W. Stimulants and doping in sport. Endocrinol Metab Clin North Am. 2010 Mar;39(1):89-105, ix. doi: 10.1016/j.ecl.2009.10.011. PubMed PMID: 20122452. 15: Namera A, Nakamoto A, Nishida M, Saito T, Kishiyama I, Miyazaki S, Yahata M, Yashiki M, Nagao M. Extraction of amphetamines and methylenedioxyamphetamines from urine using a monolithic silica disk-packed spin column and high-performance liquid chromatography-diode array detection. J Chromatogr A. 2008 Oct 24;1208(1-2):71-5. doi: 10.1016/j.chroma.2008.08.091. Epub 2008 Sep 2. PubMed PMID: 18790482. 16: Thevis M, Sigmund G, Koch A, Guddat S, Maurer HH, Schänzer W. Doping control analysis of methoxyphenamine using liquid chromatography-tandem mass spectrometry. Eur J Mass Spectrom (Chichester). 2008;14(3):145-52. doi: 10.1255/ejms.926. PubMed PMID: 18708694. 17: Yang JL, Satuito CG, Bao WY, Kitamura H. Induction of metamorphosis of pediveliger larvae of the mussel Mytilus galloprovincialis Lamarck, 1819 using neuroactive compounds, KCl, NH4Cl and organic solvents. Biofouling. 2008;24(6):461-70. doi: 10.1080/08927010802340309. PubMed PMID: 18701989. 18: Miyaguchi H, Tokeshi M, Kikutani Y, Hibara A, Inoue H, Kitamori T. Microchip-based liquid-liquid extraction for gas-chromatography analysis of amphetamine-type stimulants in urine. J Chromatogr A. 2006 Sep 29;1129(1):105-10. Epub 2006 Jul 25. PubMed PMID: 16872620. 19: Hsieh YC, Whang CW. Analysis of ethambutol and methoxyphenamine by capillary electrophoresis with electrochemiluminescence detection. J Chromatogr A. 2006 Jul 28;1122(1-2):279-82. Epub 2006 Jun 22. PubMed PMID: 16797572. 20: Myung SW, Yoon SH, Kim M. Analysis of benzene ethylamine derivatives in urine using the programmable dynamic liquid-phase microextraction (LPME) device. Analyst. 2003 Dec;128(12):1443-6. Epub 2003 Nov 18. PubMed PMID: 14737229.