MedKoo Cat#: 584509 | Name: AZ 5704
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZ 5704 is a potent and selective ATM kinase inhibitor.

Chemical Structure

AZ 5704
AZ 5704
CAS#1941214-06-7

Theoretical Analysis

MedKoo Cat#: 584509

Name: AZ 5704

CAS#: 1941214-06-7

Chemical Formula: C23H23FN6O2

Exact Mass: 434.1867

Molecular Weight: 434.48

Elemental Analysis: C, 63.58; H, 5.34; F, 4.37; N, 19.34; O, 7.36

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
25mg USD 1,150.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
AZ 5704; AZ5704; AZ-5704
IUPAC/Chemical Name
7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide
InChi Key
XHNKFGYYGPLYPT-ZDUSSCGKSA-N
InChi Code
InChI=1S/C23H23FN6O2/c1-13(20-6-7-30(2)29-20)28-22-17-8-16(14-4-5-15(12-32-3)26-10-14)19(24)9-21(17)27-11-18(22)23(25)31/h4-11,13H,12H2,1-3H3,(H2,25,31)(H,27,28)/t13-/m0/s1
SMILES Code
O=C(C1=C(N[C@H](C2=NN(C)C=C2)C)C3=CC(C4=CC=C(COC)N=C4)=C(F)C=C3N=C1)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 434.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Degorce et al (2016) Discovery of novel 3-quinoline carboxamides as potent, selective and orally bioavailable inhibitors of ataxia telangiectasia mutated (ATM) kinase. J.Med.Chem. 59 6281 PMID: 27259031