SC 53606 | CAS#151898-33-8 | 5-hydroxytryptamine4 receptor antagonist

MedKoo Cat#: 461887 | Name: SC 53606

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SC 53606 is a potent and selective antagonist of 5-hydroxytryptamine4 receptor.

Chemical Structure

SC 53606

CAS#151898-33-8

Theoretical Analysis

MedKoo Cat#: 461887

Name: SC 53606

CAS#: 151898-33-8

Chemical Formula: C16H19ClN4O

Exact Mass: 318.1247

Molecular Weight: 318.80

Elemental Analysis: C, 60.28; H, 6.01; Cl, 11.12; N, 17.57; O, 5.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SC 53606; SC-53606; SC53606;

IUPAC/Chemical Name

6-chloro-N-(((1S,7aS)-hexahydro-1H-pyrrolizin-1-yl)methyl)imidazo[1,2-a]pyridine-8-carboxamide

InChi Key

SKYGATVDBNOBSE-FZMZJTMJSA-N

InChi Code

InChI=1S/C16H19ClN4O/c17-12-8-13(15-18-4-7-21(15)10-12)16(22)19-9-11-3-6-20-5-1-2-14(11)20/h4,7-8,10-11,14H,1-3,5-6,9H2,(H,19,22)/t11-,14-/m0/s1

SMILES Code

O=C(C1=CC(Cl)=CN2C1=NC=C2)NC[C@H]3[C@]4([H])CCCN4CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 318.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Budhoo MR, Kellum JM. Evidence for a 5-HT4 receptor pathway mediating chloride secretion in the rat distal colon. J Surg Res. 1994 Jul;57(1):44-8. PubMed PMID: 8041147. 2: Yang DC, Goldstin B, Moormann AE, Flynn DL, Gullikson GW. SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae. J Pharmacol Exp Ther. 1993 Sep;266(3):1339-47. PubMed PMID: 8396633.