SC-50605 | CAS#138828-39-4 | LTB4 receptor antagonist

MedKoo Cat#: 461886 | Name: SC-50605

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SC-50605 is a second-generation LTB4 receptor antagonist.

Chemical Structure

SC-50605

CAS#138828-39-4

Theoretical Analysis

MedKoo Cat#: 461886

Name: SC-50605

CAS#: 138828-39-4

Chemical Formula: C30H35NO6S

Exact Mass: 537.2185

Molecular Weight: 537.67

Elemental Analysis: C, 67.02; H, 6.56; N, 2.61; O, 17.85; S, 5.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

SC-50605; SC 50605; SC50605;

IUPAC/Chemical Name

7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-(thiazol-4-yl)phenoxy)propoxy)-8-propylchromane-2-carboxylic acid

InChi Key

NFHKAMAWIQHXAT-UHFFFAOYSA-N

InChi Code

InChI=1S/C30H35NO6S/c1-3-5-22-25(11-8-20-9-12-27(30(32)33)37-28(20)22)35-14-4-15-36-26-13-10-21(24-17-38-18-31-24)29(34-2)23(26)16-19-6-7-19/h8,10-11,13,17-19,27H,3-7,9,12,14-16H2,1-2H3,(H,32,33)

SMILES Code

O=C(C1CCC2=CC=C(OCCCOC3=CC=C(C4=CSC=N4)C(OC)=C3CC5CC5)C(CCC)=C2O1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 537.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Penning TD, Djuric SW, Miyashiro JM, Yu S, Snyder JP, Spangler D, Anglin CP, Fretland DJ, Kachur JF, Keith RH, et al. Second-generation leukotriene B4 receptor antagonists related to SC-41930: heterocyclic replacement of the methyl ketone pharmacophore. J Med Chem. 1995 Mar 17;38(6):858-68. PubMed PMID: 7699700. 2: Penning TD, Djuric SW, Docter SH, Yu SS, Spangler D, Anglin CP, Fretland DJ, Kachur JF, Keith RH, Tsai BS, et al. The design and synthesis of second generation leukotriene B4 (LTB4) receptor antagonists related to SC-41930. Agents Actions. 1993;39 Spec No:C11-3. PubMed PMID: 8273545. 3: Fretland DJ, Widomski DL, Anglin CP, Penning TD, Yu S, Djuric SW. Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146. Inflammation. 1993 Jun;17(3):353-60. PubMed PMID: 8392493.