Meticrane | CAS#1084-65-7 | diuretic

MedKoo Cat#: 592962 | Name: Meticrane

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Meticrane is a diuretic.

Chemical Structure

Meticrane

CAS#1084-65-7

Theoretical Analysis

MedKoo Cat#: 592962

Name: Meticrane

CAS#: 1084-65-7

Chemical Formula: C10H13NO4S2

Exact Mass: 275.0286

Molecular Weight: 275.34

Elemental Analysis: C, 43.62; H, 4.76; N, 5.09; O, 23.24; S, 23.29

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 295.00	2 Weeks
5g	USD 550.00	2 Weeks

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Related CAS #

No Data

Synonym

Meticrane

IUPAC/Chemical Name

2H-1-Benzothiopyran-7-sulfonamide, 3,4-dihydro-6-methyl-, 1,1-dioxide (9CI)

InChi Key

FNQQBFNIYODEMB-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H13NO4S2/c1-7-5-8-3-2-4-16(12,13)10(8)6-9(7)17(11,14)15/h5-6H,2-4H2,1H3,(H2,11,14,15)

SMILES Code

O=S(C1=C(C)C=C(C2=C1)CCCS2(=O)=O)(N)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMSO	52.5	190.68
	Water	0.1	0.36

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 275.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Boissier JR, Hirtz J, Dumont C, Gérardin A. [Resorption, distribution, excretion and metabolism in rat of a new diuretic: meticrane]. Ann Pharm Fr. 1970 Jul-Aug;28(7):497-509. French. PubMed PMID: 5485056. 2: Linquette M, Decoulx M. [Clinical trial of a new diuretic: meticrane]. Lille Med. 1968 Jan;13(1):Suppl:13-6. French. PubMed PMID: 5745602.