MedKoo Cat#: 471010 | Name: CU-CPT8m
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CU-CPT8m is an antagonist of toll-like receptor 8 (TLR8; Kd = 220 nM; IC50 = 67 nM in a reporter assay)

Chemical Structure

CU-CPT8m
CU-CPT8m
CAS#125079-83-6

Theoretical Analysis

MedKoo Cat#: 471010

Name: CU-CPT8m

CAS#: 125079-83-6

Chemical Formula: C14H12N4O

Exact Mass: 252.1011

Molecular Weight: 252.28

Elemental Analysis: C, 66.65; H, 4.79; N, 22.21; O, 6.34

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 1,050.00 2 Weeks
100mg USD 1,650.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
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Synonym
CU-CPT-8m; CU-CPT 8m; CU-CPT8m; CUCPT-8m; CU CPT 8m; CU-CPT 8m;
IUPAC/Chemical Name
7-(m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChi Key
HNKGGVGQAVODNJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H12N4O/c1-9-3-2-4-10(7-9)12-5-6-16-14-11(13(15)19)8-17-18(12)14/h2-8H,1H3,(H2,15,19)
SMILES Code
CC1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C(=O)N
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Zhang, S., Hu, Z., Tanji, H., et al. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat. Chem. Biol. 14(1), 58-64 (2018).