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MedKoo Cat#: 461837 | Name: Thiobencarb
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thiobencarb is a thiocarbamate cholinesterase inhibitor that is used as a pre-emergence herbicide.

Chemical Structure

Thiobencarb
Thiobencarb
CAS#28249-77-6

Theoretical Analysis

MedKoo Cat#: 461837

Name: Thiobencarb

CAS#: 28249-77-6

Chemical Formula: C12H16ClNOS

Exact Mass: 257.0641

Molecular Weight: 257.77

Elemental Analysis: C, 55.91; H, 6.26; Cl, 13.75; N, 5.43; O, 6.21; S, 12.44

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
5g USD 1,250.00 2 Weeks
10g USD 2,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Thiobencarb; Benthiocarb; Saturn; Siacarb; Thiobencarbe;
IUPAC/Chemical Name
S-(4-chlorobenzyl) diethylcarbamothioate
InChi Key
QHTQREMOGMZHJV-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H16ClNOS/c1-3-14(4-2)12(15)16-9-10-5-7-11(13)8-6-10/h5-8H,3-4,9H2,1-2H3
SMILES Code
O=C(SCC1=CC=C(Cl)C=C1)N(CC)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 257.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shimasaki Y, Tsuyama M, Tasmin R, Qiu X, Shimizu M, Sato Y, Yamasaki Y, Kato-Unoki Y, Nukata A, Nakashima T, Ichinose H, Wariishi H, Honjo T, Oshima Y. Thiobencarb herbicide reduces growth, photosynthetic activity, and amount of Rieske iron-sulfur protein in the diatom Thalassiosira pseudonana. J Biochem Mol Toxicol. 2013 Sep;27(9):437-44. doi: 10.1002/jbt.21505. Epub 2013 Jun 25. PubMed PMID: 23801610. 2: Bhowmick S, Das R, Das AC. Effect of thiobencarb and pretilachlor on microorganisms in relation to mineralization of C and N in the Gangetic alluvial soil of West Bengal. Environ Monit Assess. 2014 Oct;186(10):6849-56. doi: 10.1007/s10661-014-3893-4. Epub 2014 Jul 5. PubMed PMID: 24996621. 3: Mahmoudi M, Rahnemaie R, Es-haghi A, Malakouti MJ. Kinetics of degradation and adsorption-desorption isotherms of thiobencarb and oxadiargyl in calcareous paddy fields. Chemosphere. 2013 May;91(7):1009-17. doi: 10.1016/j.chemosphere.2013.01.077. Epub 2013 Feb 22. PubMed PMID: 23461836. 4: Barman S, Das AC. Residual effect of pre-emergence herbicides on microbial activities in relation to mineralization of C, N and P in the Gangetic alluvial soil of West Bengal, India. Environ Monit Assess. 2015 Jul;187(7):465. doi: 10.1007/s10661-015-4698-9. Epub 2015 Jun 26. PubMed PMID: 26113205. 5: Sapari P, Ismail BS. Pollution levels of thiobencarb, propanil, and pretilachlor in rice fields of the muda irrigation scheme, Kedah, Malaysia. Environ Monit Assess. 2012 Oct;184(10):6347-56. doi: 10.1007/s10661-011-2424-9. Epub 2011 Nov 18. PubMed PMID: 22089624. 6: Saka M, Tada N, Kamata Y. Application of an amphibian (Silurana tropicalis) metamorphosis assay to the testing of the chronic toxicity of three rice paddy herbicides: simetryn, mefenacet, and thiobencarb. Ecotoxicol Environ Saf. 2013 Jun;92:135-43. doi: 10.1016/j.ecoenv.2013.03.023. Epub 2013 Apr 15. PubMed PMID: 23597675. 7: Rezaee R, Hassanzadeh-Khayyat M, Mehri F, Khashyarmanesh Z, Moallemzadeh H, Karimi G. Determination of parathion, aldicarb, and thiobencarb in tap water and bottled mineral water in Mashhad, Iran. Drug Chem Toxicol. 2012 Apr;35(2):192-8. doi: 10.3109/01480545.2011.589847. Epub 2011 Sep 22. PubMed PMID: 21939365. 8: Saka M. Acute toxicity of rice paddy herbicides simetryn, mefenacet, and thiobencarb to Silurana tropicalis tadpoles. Ecotoxicol Environ Saf. 2010 Sep;73(6):1165-9. doi: 10.1016/j.ecoenv.2010.05.008. PubMed PMID: 20537391. 9: Xia J. Response of growth, photosynthesis and photoinhibition of the edible cyanobacterium Nostoc sphaeroides colonies to thiobencarb herbicide. Chemosphere. 2005 Apr;59(4):561-6. Epub 2005 Jan 26. PubMed PMID: 15788179. 10: Fernández-Vega C, Sancho E, Ferrando MD. Energy reserves mobilization in the yellow eel as herbicide exposure effect. Chemosphere. 2015 Sep;135:94-100. doi: 10.1016/j.chemosphere.2015.03.032. Epub 2015 Apr 27. PubMed PMID: 25917606. 11: Das AC, Barman S, Das R. Effect of Pre-emergence Herbicides on Microbial Biomass and Biochemical Processes in a Typic Fluvaquent Soil Amended with Farm Yard Manure. Bull Environ Contam Toxicol. 2015 Sep;95(3):395-400. doi: 10.1007/s00128-015-1571-z. Epub 2015 Jun 6. PubMed PMID: 26048439. 12: Doran G, Eberbach P, Helliwell S. The mobility of thiobencarb and fipronil in two flooded rice-growing soils. J Environ Sci Health B. 2008 Aug;43(6):490-7. doi: 10.1080/03601230802174631. PubMed PMID: 18665985. 13: Phong TK, Nhung DT, Motobayashi T, Watanabe H. Behavior of simetryn and thiobencarb in the plough zone of rice fields. Bull Environ Contam Toxicol. 2009 Dec;83(6):794-8. doi: 10.1007/s00128-009-9810-9. PubMed PMID: 19585064. 14: Das AC, Das R, Bhowmick S. Non-symbiotic N2-fixation and phosphate-solubility in Gangetic alluvial soil as influenced by pre-emergence herbicide residues. Chemosphere. 2015 Sep;135:202-7. doi: 10.1016/j.chemosphere.2015.04.039. Epub 2015 May 15. PubMed PMID: 25957139. 15: Cashman JR, Olsen LD, Nishioka RS, Gray ES, Bern HA. S-oxygenation of thiobencarb (Bolero) in hepatic preparations from striped bass (Morone saxatilis) and mammalian systems. Chem Res Toxicol. 1990 Sep-Oct;3(5):433-40. PubMed PMID: 2133094. 16: Sancho E, Fernández-Vega C, Ferrando MD, Andreu-Moliner E. Eel ATPase activity as biomarker of thiobencarb exposure. Ecotoxicol Environ Saf. 2003 Nov;56(3):434-41. PubMed PMID: 14575684. 17: Sancho E, Sánchez M, Ferrando MD, Andreu-Moliner E. Effects of thiobencarb herbicide to an alga (Nannochloris oculata) and the cladoceran (Daphnia magna). J Environ Sci Health B. 2001 Jan;36(1):55-65. PubMed PMID: 11281255. 18: Battah MG, Shabana EF, Kobbia IA, Eladel HM. Differential effects of thiobencarb toxicity on growth and photosynthesis of Anabaena variabilis with changes in phosphate level. Ecotoxicol Environ Saf. 2001 Jul;49(3):235-9. PubMed PMID: 11440476. 19: Raimondo S, McKenney CL Jr. Projected population-level effects of thiobencarb exposure on the mysid, Americamysis bahia, and extinction probability in a concentration-decay exposure system. Environ Toxicol Chem. 2005 Mar;24(3):564-72. PubMed PMID: 15779755. 20: Burdett AS, Stevens MM, Macmillan DL. Laboratory and field studies on the effect of molinate, clomazone, and thiobencarb on nontarget aquatic invertebrates. Environ Toxicol Chem. 2001 Oct;20(10):2229-36. PubMed PMID: 11596755.