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MedKoo Cat#: 558587 | Name: Magnesium acetylsalicylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Magnesium acetylsalicylate is a magnesium salt used as an analgesic and antipyretic.

Chemical Structure

Magnesium acetylsalicylate
Magnesium acetylsalicylate
CAS#132-49-0

Theoretical Analysis

MedKoo Cat#: 558587

Name: Magnesium acetylsalicylate

CAS#: 132-49-0

Chemical Formula: C18H14MgO8

Exact Mass: 382.0500

Molecular Weight: 382.60

Elemental Analysis: C, 56.51; H, 3.69; Mg, 6.35; O, 33.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Magnesium acetylsalicylate; Fyracyl; Juridin; Kowefin; Macetocyl; Magisal;
IUPAC/Chemical Name
Magnesium o-acetylsalicylate
InChi Key
RBLKLJDYAHZCFW-UHFFFAOYSA-L
InChi Code
InChI=1S/2C9H8O4.Mg/c2*1-6(10)13-8-5-3-2-4-7(8)9(11)12;/h2*2-5H,1H3,(H,11,12);/q;;+2/p-2
SMILES Code
O=C([O-])C1=CC=CC=C1OC(C)=O.O=C([O-])C2=CC=CC=C2OC(C)=O.[Mg+2]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 382.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: AWE W. [Studies on preparations containing magnesium acetylsalicylate and proposals for testing]. Arzneimittelforschung. 1957 Sep;7(9):568-72. German. PubMed PMID: 13471405. 2: Wolf FI, Di Francesco A, Covacci V, Corda D, Cittadini A. Regulation of intracellular magnesium in ascites cells: involvement of different regulatory pathways. Arch Biochem Biophys. 1996 Jul 15;331(2):194-200. PubMed PMID: 8660698. 3: Biban C, Tassani V, Toninello A, Siliprandi D, Siliprandi N. The alterations in the energy linked properties induced in rat liver mitochondria by acetylsalicylate are prevented by cyclosporin A or Mg2+. Biochem Pharmacol. 1995 Aug 8;50(4):497-500. PubMed PMID: 7646555. 4: Holmsen H, Dangelmaier CA. Evidence that the platelet plasma membrane is impermeable to calcium and magnesium complexes of A23187. A23187-induced secretion is inhibited by MG2+ and Ca2+, and requires aggregation and active cyclooxygenase. J Biol Chem. 1981 Oct 25;256(20):10449-52. PubMed PMID: 6793580. 5: Ramsay AG, Elliott HC, Haynes AM. The effect of methyl acetylsalicylate on renal tubular ionic reabsorption. Proc Soc Exp Biol Med. 1969 Oct;132(1):307-13. PubMed PMID: 5344852. 6: Tomida Y, Makino T. Prevention of small black spots on sugar-coated tablets containing aluminum acetylsalicylic acid. Drug Dev Ind Pharm. 1999 Apr;25(4):445-52. PubMed PMID: 10194599. 7: Hancock RE, Wong PG. Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane. Antimicrob Agents Chemother. 1984 Jul;26(1):48-52. PubMed PMID: 6433788; PubMed Central PMCID: PMC179915.