MedKoo Cat#: 461753 | Name: Metoxuron
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Metoxuron is a phenylurea herbicide.

Chemical Structure

Metoxuron
Metoxuron
CAS#19937-59-8

Theoretical Analysis

MedKoo Cat#: 461753

Name: Metoxuron

CAS#: 19937-59-8

Chemical Formula: C10H13ClN2O2

Exact Mass: 228.0666

Molecular Weight: 228.68

Elemental Analysis: C, 52.52; H, 5.73; Cl, 15.50; N, 12.25; O, 13.99

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Metoxuron; Dosanex; Deftor; Dosagran; Purivel; Sulerex;
IUPAC/Chemical Name
3-(3-chloro-4-methoxyphenyl)-1,1-dimethylurea
InChi Key
DSRNRYQBBJQVCW-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13ClN2O2/c1-13(2)10(14)12-7-4-5-9(15-3)8(11)6-7/h4-6H,1-3H3,(H,12,14)
SMILES Code
O=C(NC1=CC=C(OC)C(Cl)=C1)N(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Biological target:
Metoxuron is a phenylurea herbicide.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 228.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Boulkamh A, Harakat D, Sehili T, Boule P. Phototransformation of metoxuron [3-(3-chloro-4-methoxyphenyl)-1,1-dimethylurea] in aqueous solution. Pest Manag Sci. 2001 Dec;57(12):1119-26. PubMed PMID: 11802599. 2: Gudéhn A, Kolmodin-Hedman B. Sampling and determination of fenitrothion, dimethoate, mevinphos, linuron, metoxuron and trifluralin from air. J Chromatogr. 1987 Jan 30;387:420-7. PubMed PMID: 3558633. 3: Raju KR, Parthasarathy TN, Akella SR, Bhalerao UT. Spectrophotometric assay of Isoproturon and Metoxuron in technical grade and formulation samples using 3-methylbenzothiozolin-2-one hydrazone hydrochloride. Talanta. 1992 Oct;39(10):1387-90. PubMed PMID: 18965546. 4: Fabbri D, Minella M, Maurino V, Minero C, Vione D. Photochemical transformation of phenylurea herbicides in surface waters: a model assessment of persistence, and implications for the possible generation of hazardous intermediates. Chemosphere. 2015 Jan;119:601-607. doi: 10.1016/j.chemosphere.2014.07.034. Epub 2014 Aug 14. PubMed PMID: 25128892. 5: Ramakrishnam Raju K, Akella SR, Murthy JV, Bhalerao UT. Spectrophotometric determination of Isoproturon and Metoxuron using ethylacetoacetate and application to technical and formulation grade samples. Talanta. 1996 Apr;43(4):577-81. PubMed PMID: 18966521. 6: Haesaert G, Derycke V, Deroo B, Latré J. Effect of different chemical and mechanical defolation methods on the skin quality of potatoes. Commun Agric Appl Biol Sci. 2004;69(4):757-63. PubMed PMID: 15756866. 7: Bonnemoy F, Lavédrine B, Boulkamh A. Influence of UV irradiation on the toxicity of phenylurea herbicides using Microtox test. Chemosphere. 2004 Feb;54(8):1183-7. PubMed PMID: 14664847. 8: Baranowska I, Pieszko C. Derivative spectrophotometry in the analysis of mixtures of phenols and herbicides. Analyst. 2000 Dec;125(12):2335-8. PubMed PMID: 11219078. 9: Hutta M, Chalányová M, Halko R, Góra R, Dokupilová S, Rybár I. Reversed phase liquid chromatography trace analysis of pesticides in soil by on-column sample pumping large volume injection and UV detection. J Sep Sci. 2009 Jun;32(12):2034-42. doi: 10.1002/jssc.200900036. PubMed PMID: 19548212. 10: Librando V, Forte S, Sarpietro MG. Structure effect on the interaction of phenylurea herbicides with model biomembrane as an environmental mobility parameter. Environ Sci Technol. 2004 Jan 15;38(2):503-7. PubMed PMID: 14750726. 11: Langeron J, Sayen S, Couderchet M, Guillon E. Leaching potential of phenylurea herbicides in a calcareous soil: comparison of column elution and batch studies. Environ Sci Pollut Res Int. 2014 Apr;21(7):4906-13. doi: 10.1007/s11356-012-1244-y. Epub 2012 Oct 23. PubMed PMID: 23097070. 12: Navarro S, Hernández-Bastida J, Cazaña G, Pérez-Lucas G, Fenoll J. Assessment of the leaching potential of 12 substituted phenylurea herbicides in two agricultural soils under laboratory conditions. J Agric Food Chem. 2012 May 30;60(21):5279-86. doi: 10.1021/jf301094c. Epub 2012 May 18. PubMed PMID: 22578198. 13: Hooghe RJ, Devos S, Hooghe-Peters EL. Effects of selected herbicides on cytokine production in vitro. Life Sci. 2000 May 19;66(26):2519-25. PubMed PMID: 10883730. 14: Caquet T, Roucaute M, Mazzella N, Delmas F, Madigou C, Farcy E, Burgeot T, Allenou JP, Gabellec R. Risk assessment of herbicides and booster biocides along estuarine continuums in the Bay of Vilaine area (Brittany, France). Environ Sci Pollut Res Int. 2013 Feb;20(2):651-66. doi: 10.1007/s11356-012-1171-y. Epub 2012 Sep 16. PubMed PMID: 22983624. 15: Lester Y, Sharpless CM, Mamane H, Linden KG. Production of photo-oxidants by dissolved organic matter during UV water treatment. Environ Sci Technol. 2013 Oct 15;47(20):11726-33. doi: 10.1021/es402879x. Epub 2013 Sep 26. PubMed PMID: 24011169. 16: Baranowska I, Pieszko C. Determination of selected herbicides and phenols in water and soils by solid-phase extraction and high-performance liquid chromatography. J Chromatogr Sci. 2000 May;38(5):211-8. PubMed PMID: 10813519. 17: Nevo E, Snape JW, Lavie B, Beiles A. Herbicide response polymorphisms in wild emmer wheat: ecological and isozyme correlations. Theor Appl Genet. 1992 Jun;84(1-2):209-16. doi: 10.1007/BF00224002. PubMed PMID: 24203049. 18: Dommarco R, Santilio A, Fornarelli L, Rubbiani M. Simultaneous quantitative determination of thirteen urea pesticides at sub-ppb levels on a Zorbax SB-C18 column. J Chromatogr A. 1998 Nov 6;825(2):200-4. PubMed PMID: 9842721. 19: Balinova A. Solid-phase extraction followed by high-performance liquid chromatographic analysis for monitoring herbicides in drinking water. J Chromatogr. 1993 Jul 23;643(1-2):203-7. PubMed PMID: 8360301. 20: Sannino A. Determination of phenylurea herbicide residues in vegetables by liquid chromatography after gel permeation chromatography and Florisil cartridge cleanup. J AOAC Int. 1998 Sep-Oct;81(5):1048-53. PubMed PMID: 9772748.