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MedKoo Cat#: 592862 | Name: Amphoglucamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amphoglucamine is used in the combined chemotherapy of viral diseases.

Chemical Structure

Amphoglucamine
Amphoglucamine
CAS#58722-78-4

Theoretical Analysis

MedKoo Cat#: 592862

Name: Amphoglucamine

CAS#: 58722-78-4

Chemical Formula: C54H90N2O22

Exact Mass: 1118.5985

Molecular Weight: 1119.31

Elemental Analysis: C, 57.95; H, 8.11; N, 2.50; O, 31.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Amphoglucamine
IUPAC/Chemical Name
Amphotericin B, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1)
InChi Key
BMTUXPZRZGAUCT-LBUWUQBSSA-N
InChi Code
InChI=1S/C47H73NO17.C7H17NO5/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56;1-8-2-4(10)6(12)7(13)5(11)3-9/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60);4-13H,2-3H2,1H3/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+;/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+;4-,5+,6+,7+/m00/s1
SMILES Code
C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,119.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Fateeva LI. [Pharmacokinetics of amphoglucamine in an experiment]. Antibiot Med Biotekhnol. 1986 Apr;31(4):280-3. Russian. PubMed PMID: 3717925. 2: Shneĭder MA, Golovkin VI, Chizhov NP, Shtil'bans EB. [Amphoglucamine in the combined chemotherapy of viral diseases]. Vopr Virusol. 1987 Nov-Dec;32(6):736-9. Russian. PubMed PMID: 3445592. 3: Mikhaĭlova MA, Ezhkov GA. [Effectiveness of amphoglucamine in experimental candidiasis in sex hormone administration]. Antibiotiki. 1981 Jun;26(6):469-73. Russian. PubMed PMID: 7271261. 4: Mikhaĭlova MA, Ekzempliarov ON. [Effect of amphoglucamine on humoral immunity indices]. Antibiotiki. 1980 Jan;25(1):32-5. Russian. PubMed PMID: 7356298. 5: Moskovskaia MA. [Our experience treating deep mycoses with amphoglucamine]. Antibiotiki. 1981 Feb;26(2):118-20. Russian. PubMed PMID: 7212692. 6: Karimov MK. [Amphoglucamine in the treatment of mycoses of the eye]. Oftalmol Zh. 1986;(2):112-4. Russian. PubMed PMID: 3714170. 7: Liubimova LK, Ovnanian KO, Ivanova LN. [Anti-amebic effect of polyenic antibiotics]. Antibiot Med Biotekhnol. 1985 Mar;30(3):179-82. Russian. PubMed PMID: 2861787. 8: Delektorskiĭ VV, Tishchenko LD, Alita OV, Saf'ianova VM, Emel'ianova LP. [Comparative electron microscopic study of the ultrastructural changes in L. braziliensis promastigotes exposed to monomycin and amphoglucamine]. Med Parazitol (Mosk). 1982 Mar-Apr;60(2):62-5. Russian. PubMed PMID: 6806591. 9: Araviĭskiĭ RA, Shatik LI. [Effect of amphoglucamine on the functional and metabolic characteristics of macrophages]. Tr Inst Im Pastera. 1982;58:111-3. Russian. PubMed PMID: 6764978. 10: Potyl'chanskaia OL, Araviĭskiĭ RA. [Combined chemotherapy of experimental generalized candidiasis]. Antibiot Med Biotekhnol. 1987 Oct;32(10):778-81. Russian. PubMed PMID: 3426181. 11: Titov AV, Tarasova OV, Slobodskaia VV, Vavilin GI. [Effect of polyene antibiotics on the development of alcoholic-dietary fatty degeneration of the liver in rats]. Antibiotiki. 1982 Dec;27(12):42-6. Russian. PubMed PMID: 7165293. 12: Bahukova TA, Dobrodeeva LK. [Role of fungi belonging to the genus Candida in the etiology of nonspecific pulmonary diseases]. Antibiot Khimioter. 1996 Jun;41(6):44-8. Russian. PubMed PMID: 9054329. 13: Boĭko GI, Sosnin GP, Adarchenko AA, Moroz GS. [Sensitivity of Candida strains to polyenic antibiotics in the treatment of oral candidiasis]. Antibiotiki. 1984 Nov;29(11):869-72. Russian. PubMed PMID: 6395795. 14: Rodrigues KM, Oliveira MP, Maretti-Mira AC, Oliveira-Neto MP, Mattos MS, Silva L, Soares DA, Dolci EL, Perico RA, Pirmez C. Influence of the Notch system in the therapeutic response of American tegumentary leishmaniasis. Br J Dermatol. 2011 Jun;164(6):1228-34. doi: 10.1111/j.1365-2133.2011.10240.x. Epub 2011 May 17. PubMed PMID: 21299543. 15: Zheludkov MM, Gubina EA, Lebedeva IK, D'iakov SI. [Elaboration of a rapid method of determining the sensitivity of Brucella to antibiotics]. Antibiot Khimioter. 1992 May;37(5):12-4. Russian. PubMed PMID: 1417320. 16: Bogdanov VV. [Effect of terrilytin on antifungal antibiotic activity]. Antibiotiki. 1978 Jul;23(7):622-5. Russian. PubMed PMID: 354511. 17: Sheviakov MA, Antonov VB. [Esophageal candidiasis after gastric resection]. Vestn Khir Im I I Grek. 1994 Jan-Feb;152(1-2):131-3. Russian. PubMed PMID: 7701729. 18: Daniliak IG, Plakhotnaia GA. [A case of successful treatment of bronchopulmonary aspergillosis]. Ter Arkh. 1987;59(1):108-9. Russian. PubMed PMID: 3563905. 19: Lisochkin BG. [Dynamics of the morphological changes in muscle tissue after intramuscular administration of polyene antibiotics]. Tr Inst Im Pastera. 1982;58:120-2. Russian. PubMed PMID: 7187547. 20: Delektorskiĭ VV, Sheklakov ND, Golodova OA. [Ultrastructural changes in Candida albicans exposed to polyene antibiotics]. Vestn Dermatol Venerol. 1980 Nov;(11):14-6. Russian. PubMed PMID: 7003976.