MedKoo Cat#: 563686 | Name: IMB-10
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.

Chemical Structure

IMB-10
IMB-10
CAS#307525-40-2

Theoretical Analysis

MedKoo Cat#: 563686

Name: IMB-10

CAS#: 307525-40-2

Chemical Formula: C19H15NOS2

Exact Mass: 337.0595

Molecular Weight: 337.45

Elemental Analysis: C, 67.63; H, 4.48; N, 4.15; O, 4.74; S, 19.00

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
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Related CAS #
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Synonym
IMB-10; IMB 10; IMB10;
IUPAC/Chemical Name
5-(3-Phenyl-allylidene)-2-thioxo-3-o-tolyl-thiazolidin-4-one
InChi Key
UYZLENPCNZVWQZ-DNZSEPECSA-N
InChi Code
InChI=1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13-
SMILES Code
O=C1N(C2=CC=CC=C2C)C(S/C1=C\C=C\C3=CC=CC=C3)=S
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 337.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Suojanen J, Salo T, Sorsa T, Koivunen E. AlphaMbeta2 integrin modulator exerts antitumor activity in vivo. Anticancer Res. 2007 Nov-Dec;27(6B):3775-81. PubMed PMID: 18225532. 2: Björklund M, Aitio O, Stefanidakis M, Suojanen J, Salo T, Sorsa T, Koivunen E. Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment. Biochemistry. 2006 Mar 7;45(9):2862-71. PubMed PMID: 16503641.