Samarcandin | CAS#28699-16-3 | sesquiterpene-coumarin

MedKoo Cat#: 461742 | Name: Samarcandin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Samarcandin is a natural sesquiterpene-coumarin that is isolated from F. assa-foetida.

Chemical Structure

Samarcandin

CAS#28699-16-3

Theoretical Analysis

MedKoo Cat#: 461742

Name: Samarcandin

CAS#: 28699-16-3

Chemical Formula: C24H32O5

Exact Mass: 400.2250

Molecular Weight: 400.51

Elemental Analysis: C, 71.97; H, 8.05; O, 19.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Samarcandin;

IUPAC/Chemical Name

7-(((1S,2R,4aR,6R,8aS)-2,6-dihydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl)methoxy)-2H-chromen-2-one

InChi Key

WNANPKYNOALKIV-XARGLDOUSA-N

InChi Code

InChI=1S/C24H32O5/c1-22(2)18-9-12-24(4,27)19(23(18,3)11-10-20(22)25)14-28-16-7-5-15-6-8-21(26)29-17(15)13-16/h5-8,13,18-20,25,27H,9-12,14H2,1-4H3/t18-,19+,20+,23-,24+/m0/s1

SMILES Code

O=C1C=CC2=C(O1)C=C(OC[C@H]3[C@](C)(O)CC[C@@]4([H])C(C)(C)[C@H](O)CC[C@]34C)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 400.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ghoran SH, Atabaki V, Babaei E, Olfatkhah SR, Dusek M, Eigner V, Soltani A, Khalaji AD. Isolation, spectroscopic characterization, X-ray, theoretical studies as well as in vitro cytotoxicity of Samarcandin. Bioorg Chem. 2016 Jun;66:27-32. doi: 10.1016/j.bioorg.2016.03.005. Epub 2016 Mar 15. PubMed PMID: 26998943. 2: Asghari J, Atabaki V, Baher E, Mazaheritehrani M. Identification of sesquiterpene coumarins of oleo-gum resin of Ferula assa-foetida L. from the Yasuj region. Nat Prod Res. 2016;30(3):350-3. doi: 10.1080/14786419.2015.1050669. Epub 2015 Jul 2. PubMed PMID: 26134757. 3: Ghannadi A, Fattahian K, Shokoohinia Y, Behbahani M, Shahnoush A. Anti-Viral Evaluation of Sesquiterpene Coumarins from Ferula assa-foetida against HSV-1. Iran J Pharm Res. 2014 Spring;13(2):523-30. PubMed PMID: 25237347; PubMed Central PMCID: PMC4157027. 4: Kasaian J, Mosaffa F, Behravan J, Masullo M, Piacente S, Iranshahi M. Modulation of Multidrug Resistance Protein 2 Efflux in the Cisplatin Resistance Human Ovarian Carcinoma Cells A2780/RCIS by Sesquiterpene Coumarins. Phytother Res. 2016 Jan;30(1):84-9. doi: 10.1002/ptr.5504. Epub 2015 Oct 27. PubMed PMID: 26503061. 5: Abd El-Razek MH, Ohta S, Ahmed AA, Hirata T. Sesquiterpene coumarins from the roots of Ferula assa-foetida. Phytochemistry. 2001 Dec;58(8):1289-95. PubMed PMID: 11738424.