MedKoo Cat#: 599283 | Name: LS 34

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LS 34 is a bioactive chemical.

Chemical Structure

LS 34
LS 34
CAS#83726-79-8

Theoretical Analysis

MedKoo Cat#: 599283

Name: LS 34

CAS#: 83726-79-8

Chemical Formula: C12H16BrN3S2

Exact Mass:

Molecular Weight: 346.30

Elemental Analysis: C, 41.62; H, 4.66; Br, 23.07; N, 12.13; S, 18.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
LS 34; LS34; LS-34;
IUPAC/Chemical Name
N,N-dimethyl-2-((4-(thiophen-2-yl)pyrimidin-2-yl)thio)ethan-1-amine hydrobromide
InChi Key
RNJTVJSPZGGSHQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H15N3S2.BrH/c1-15(2)7-9-17-12-13-6-5-10(14-12)11-4-3-8-16-11;/h3-6,8H,7,9H2,1-2H3;1H
SMILES Code
CN(C)CCSC1=NC=CC(C2=CC=CS2)=N1.[H]Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Horwitz MJ, Augustine M, Khan L, Martin E, Oakley CC, Carneiro RM, Tedesco MB, Laslavic A, Sereika SM, Bisello A, Garcia-Ocaña A, Gundberg CM, Cauley JA, Stewart AF. A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: the PrOP study. J Bone Miner Res. 2013 Nov;28(11):2266-76. doi: 10.1002/jbmr.1978. Erratum in: J Bone Miner Res. 2014 Mar;29(3):770. Kahn, Leila [corrected to Khan, Leila]. PubMed PMID: 23661240; PubMed Central PMCID: PMC3789852. 2: Zhang HL, Liu XM, He Y. [Measurement of soil organic matter and available K based on SPA-LS-SVM]. Guang Pu Xue Yu Guang Pu Fen Xi. 2014 May;34(5):1348-51. Chinese. PubMed PMID: 25095436. 3: Bachert C, Mannent L, Naclerio RM, Mullol J, Ferguson BJ, Gevaert P, Hellings P, Jiao L, Wang L, Evans RR, Pirozzi G, Graham NM, Swanson B, Hamilton JD, Radin A, Gandhi NA, Stahl N, Yancopoulos GD, Sutherland ER. Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial. JAMA. 2016 Feb 2;315(5):469-79. doi: 10.1001/jama.2015.19330. PubMed PMID: 26836729. 4: Muraki S, Yoshimura N, Akune T, Tanaka S, Takahashi I, Fujiwara S. Prevalence, incidence and progression of lumbar spondylosis by gender and age strata. Mod Rheumatol. 2014 Jul;24(4):657-61. doi: 10.3109/14397595.2013.843761. Epub 2013 Nov 5. PubMed PMID: 24252032. 5: Monteiro S, Boal Carvalho P, Dias de Castro F, Magalhães J, Machado F, Moreira MJ, Rosa B, Cotter J. Capsule Endoscopy: Diagnostic Accuracy of Lewis Score in Patients with Suspected Crohn's Disease. Inflamm Bowel Dis. 2015 Oct;21(10):2241-6. doi: 10.1097/MIB.0000000000000517. PubMed PMID: 26197449. 6: Yamamoto N, Okano K, Oshima M, Akamoto S, Fujiwara M, Tani J, Miyoshi H, Yoneyama H, Masaki T, Suzuki Y. Laparoscopic splenectomy for patients with liver cirrhosis: Improvement of liver function in patients with Child-Pugh class B. Surgery. 2015 Dec;158(6):1538-44. doi: 10.1016/j.surg.2015.05.008. Epub 2015 Jun 10. PubMed PMID: 26070848. 7: Sun XL, Liang LW, Cao H, Men Q, Hou KZ, Chen Z, Zhao YE. Liver reserve function assessment by acoustic radiation force impulse imaging. World J Gastroenterol. 2015 Aug 28;21(32):9648-55. doi: 10.3748/wjg.v21.i32.9648. PubMed PMID: 26327773; PubMed Central PMCID: PMC4548126. 8: Rosengren L, Brogårdh C, Jacobsson L, Lexell J. Life satisfaction and associated factors in persons with mild to moderate Parkinson's disease. NeuroRehabilitation. 2016 Jun 23;39(2):285-94. doi: 10.3233/NRE-161359. PubMed PMID: 27341371. 9: Kołodziejczyk W, Gałecki T, Łazicka-Gałecka M, Szaflik J. Comparison of the biometric measurements obtained using noncontact optical biometers LenStar LS 900 and IOL Master V.5. Klin Oczna. 2011;113(1-3):47-51. PubMed PMID: 21853951. 10: Potthoff A, Schettler A, Attia D, Schlue J, Schmitto JD, Fegbeutel C, Strüber M, Haverich A, Manns MP, Wedemeyer H, Gebel M, Schneider A. Liver stiffness measurements and short-term survival after left ventricular assist device implantation: A pilot study. J Heart Lung Transplant. 2015 Dec;34(12):1586-94. doi: 10.1016/j.healun.2015.05.022. Epub 2015 Jun 11. PubMed PMID: 26169664. 11: Paggiosi MA, Peel NF, Eastell R. The impact of glucocorticoid therapy on trabecular bone score in older women. Osteoporos Int. 2015 Jun;26(6):1773-80. doi: 10.1007/s00198-015-3078-1. Epub 2015 Mar 6. PubMed PMID: 25743176. 12: Lisi M, Cameli M, Righini FM, Malandrino A, Tacchini D, Focardi M, Tsioulpas C, Bernazzali S, Tanganelli P, Maccherini M, Mondillo S, Henein MY. RV Longitudinal Deformation Correlates With Myocardial Fibrosis in Patients With End-Stage Heart Failure. JACC Cardiovasc Imaging. 2015 May;8(5):514-522. doi: 10.1016/j.jcmg.2014.12.026. Epub 2015 Apr 15. PubMed PMID: 25890585. 13: Wang M, Zhang M, Li J, Zhou J, Wu Z, Peng B. Risk factors of portal vein thrombosis in patients with beta thalassemia major after splenectomy: laparoscopic versus open procedure. Hepatogastroenterology. 2014 Jan-Feb;61(129):48-54. PubMed PMID: 24895792. 14: Cain B, Jones JC, Holásková I, Freeman L, Pierce B. Feasibility for Measuring Transverse Area Ratios and Asymmetry of Lumbosacral Region Paraspinal Muscles in Working Dogs Using Computed Tomography. Front Vet Sci. 2016 May 12;3:34. doi: 10.3389/fvets.2016.00034. eCollection 2016. PubMed PMID: 27243022; PubMed Central PMCID: PMC4867674. 15: Metzger J, Pfahler S, Distl O. Variant detection and runs of homozygosity in next generation sequencing data elucidate the genetic background of Lundehund syndrome. BMC Genomics. 2016 Aug 2;17:535. doi: 10.1186/s12864-016-2844-6. PubMed PMID: 27485430; PubMed Central PMCID: PMC4971756. 16: Wu Z, Zhou J, Wang X, Li YB, Niu T, Peng B. Laparoscopic splenectomy for treatment of splenic marginal zone lymphoma. World J Gastroenterol. 2013 Jun 28;19(24):3854-60. doi: 10.3748/wjg.v19.i24.3854. PubMed PMID: 23840125; PubMed Central PMCID: PMC3699034. 17: Liu XM, Zhang HL. [Rapid determination of COD in aquaculture water based on LS-SVM with ultraviolet/visible spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi. 2014 Oct;34(10):2804-7. Chinese. PubMed PMID: 25739229. 18: Boero V, Brambilla M, Sipio E, Liverani CA, Di Martino M, Agnoli B, Libutti G, Cribiù FM, Del Gobbo A, Ragni E, Bolis G. Vulvar lichen sclerosus: A new regenerative approach through fat grafting. Gynecol Oncol. 2015 Dec;139(3):471-5. doi: 10.1016/j.ygyno.2015.10.014. Epub 2015 Oct 21. PubMed PMID: 26499935. 19: Vieira-Baptista P, Lima-Silva J, Cavaco-Gomes J, Beires J, Martinez-de-Oliveira J. What differentiates symptomatic from asymptomatic women with lichen sclerosus? Gynecol Obstet Invest. 2015;79(4):263-8. doi: 10.1159/000367788. Epub 2014 Oct 21. PubMed PMID: 25342279. 20: Moreira L, Muñoz J, Cuatrecasas M, Quintanilla I, Leoz ML, Carballal S, Ocaña T, López-Cerón M, Pellise M, Castellví-Bel S, Jover R, Andreu M, Carracedo A, Xicola RM, Llor X, Boland CR, Goel A, Castells A, Balaguer F; Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer. Cancer. 2015 May 1;121(9):1395-404. doi: 10.1002/cncr.29190. Epub 2014 Dec 29. PubMed PMID: 25557234.