MedKoo Cat#: 592829 | Name: Malouetine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Malouetine is a Bis-quaternary steroidal diamine.

Chemical Structure

Malouetine
Malouetine
CAS#10308-44-8

Theoretical Analysis

MedKoo Cat#: 592829

Name: Malouetine

CAS#: 10308-44-8

Chemical Formula: C27H52I2N2

Exact Mass: 658.2220

Molecular Weight: 658.54

Elemental Analysis: C, 49.25; H, 7.96; I, 38.54; N, 4.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
IUPAC/Chemical Name
Ammonium, 5-alpha-pregnan-3-beta,20-alpha-ylenebis(trimethyl-, diiodide
InChi Key
ZKPCQHGEQUQGJK-JEGPABFXSA-L
InChi Code
InChI=1S/C27H52N2.2HI/c1-19(28(4,5)6)23-12-13-24-22-11-10-20-18-21(29(7,8)9)14-16-26(20,2)25(22)15-17-27(23,24)3;;/h19-25H,10-18H2,1-9H3;2*1H/q+2;;/p-2/t19?,20-,21?,22?,23+,24?,25?,26-,27+;;/m0../s1
SMILES Code
CC([N+](C)(C)C)[C@H]1CCC2C3CC[C@@]4([H])CC([N+](C)(C)C)CC[C@]4(C)C3CC[C@]12C.[I-].[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 658.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gourevitch MI, Sempere R, Parello J. UV spectroscopic studies of the binding of malouetine to double-stranded DNA. Biochimie. 1981 Oct;63(10):743-54. PubMed PMID: 7306581. 2: Brassart B, Gomez D, De Cian A, Paterski R, Montagnac A, Qui KH, Temime-Smaali N, Trentesaux C, Mergny JL, Gueritte F, Riou JF. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells. Mol Pharmacol. 2007 Sep;72(3):631-40. Epub 2007 Jun 22. PubMed PMID: 17586599. 3: HUU LAINE FK, PINTO SCOGNAMIGLIO W. [CURARIZING ACTIVITY OF 3-BETA,20-ALPHA-BISTRIMETHYLAMMONIUM-5-ALPHA-PREGNANE DICHLORIDE (MALOUETINE) AND OF ITS STEREOISOMERS]. Arch Int Pharmacodyn Ther. 1964 Jan 1;147:209-19. French. PubMed PMID: 14116930. 4: JANOT MM, LAINE F, GOUTAREL R. [Steroid alkaloids. V. Alkaloids of Malouetia bequaertiana E. Woodson (Apocynaceae): funtuphyllamine B and malouetine. Preliminary communication]. Ann Pharm Fr. 1960 Sep;18:673-7. French. PubMed PMID: 13789457. 5: McKenzie AG. Prelude to pancuronium and vecuronium. Anaesthesia. 2000 Jun;55(6):551-6. PubMed PMID: 10866718.