Lotifazole | CAS#71119-10-3 | non-steroidal anti-inflammatory

MedKoo Cat#: 599257 | Name: Lotifazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lotifazole is a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum.

Chemical Structure

Lotifazole

CAS#71119-10-3

Theoretical Analysis

MedKoo Cat#: 599257

Name: Lotifazole

CAS#: 71119-10-3

Chemical Formula: C12H9Cl3N2O2S

Exact Mass: 349.9450

Molecular Weight: 351.62

Elemental Analysis: C, 40.99; H, 2.58; Cl, 30.25; N, 7.97; O, 9.10; S, 9.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lotifazole; Lotifazolum; NSC 358482; NSC-358482; NSC358482; F 1686; F-1686; F1686;

IUPAC/Chemical Name

2,2,2-trichloroethyl (4-phenylthiazol-2-yl)carbamate

InChi Key

SMQXDOVGKKMUIZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H9Cl3N2O2S/c13-12(14,15)7-19-11(18)17-10-16-9(6-20-10)8-4-2-1-3-5-8/h1-6H,7H2,(H,16,17,18)

SMILES Code

O=C(OCC(Cl)(Cl)Cl)NC1=NC(C2=CC=CC=C2)=CS1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 351.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tarayre JP, Caillol V, Barbara M, Villanova G, Bru M, Aliaga M, Lauressergues H. Lotifazole (F 1686), a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum. Agents Actions. 1984 Jan;14(1):93-101. PubMed PMID: 6702514. 2: Andreani A, Rambaldi M, Locatelli A, Fraccari A, Bossa R, Galatulas I. Potential antitumor agents XIX [1]. Synthesis and antitumor activity of tricyclic compounds related to lotifazole. Pharm Acta Helv. 1992;67(8):234-6. PubMed PMID: 1384067.