MedKoo Cat#: 563678 | Name: Caylin-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Caylin-1 is a Mdm2 inhibitor, an analog of Nutlin-3.

Chemical Structure

Caylin-1
Caylin-1
CAS#1207480-88-3

Theoretical Analysis

MedKoo Cat#: 563678

Name: Caylin-1

CAS#: 1207480-88-3

Chemical Formula: C30H28Cl4N4O4

Exact Mass: 648.0865

Molecular Weight: 650.37

Elemental Analysis: C, 55.40; H, 4.34; Cl, 21.80; N, 8.61; O, 9.84

Price and Availability

Size Price Availability Quantity
1mg USD 285.00 2 Weeks
5mg USD 750.00 2 Weeks
10mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
Caylin-1; Caylin 1; Caylin1; Caylin;
IUPAC/Chemical Name
rel-4-[[(4R,5S)-4,5-Bis(3,4-dichlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone
InChi Key
SOQGENPVVRSGAY-IZLXSDGUSA-N
InChi Code
InChI=1S/C30H28Cl4N4O4/c1-16(2)42-25-14-19(41-3)6-7-20(25)29-36-27(17-4-8-21(31)23(33)12-17)28(18-5-9-22(32)24(34)13-18)38(29)30(40)37-11-10-35-26(39)15-37/h4-9,12-14,16,27-28H,10-11,15H2,1-3H3,(H,35,39)/t27-,28+/m1/s1
SMILES Code
O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C(Cl)=C3)[C@@H](C4=CC=C(Cl)C(Cl)=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 650.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Verma R, Rigatti MJ, Belinsky GS, Godman CA, Giardina C. DNA damage response to the Mdm2 inhibitor nutlin-3. Biochem Pharmacol. 2010 Feb 15;79(4):565-74. doi: 10.1016/j.bcp.2009.09.020. PubMed PMID: 19788889; PubMed Central PMCID: PMC2794967.