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MedKoo Cat#: 592820 | Name: Ammifurin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ammifurin is a Furocoumarin mixture used in treatment of vitiligo.

Chemical Structure

Ammifurin
Ammifurin
CAS#8015-48-3

Theoretical Analysis

MedKoo Cat#: 592820

Name: Ammifurin

CAS#: 8015-48-3

Chemical Formula: C25H18O9

Exact Mass: 462.0951

Molecular Weight: 462.41

Elemental Analysis: C, 64.94; H, 3.92; O, 31.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ammifurin
IUPAC/Chemical Name
4,9-Dimethoxy-7H-furo(3,2-g)(1)benzopyran-7-one mixt. with 4-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one
InChi Key
GIQRBVVYHBZHIU-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H10O5.C12H8O4/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11;1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h3-6H,1-2H3;2-6H,1H3
SMILES Code
COc(c(OC(C=C1)=O)c1c2OC)c3c2cco3.COc(c(C=CC(O4)=O)c4c5)c6c5occ6
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 462.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: INIAKHINA AV. [EXPERIENCE IN THE USE OF AMMIFURIN AND BEROXAN IN THE TREATMENT OF ALOPECIA AREATA]. Vestn Dermatol Venerol. 1964 Jan;38:59-61. Russian. PubMed PMID: 14177921. 2: VINOKUROV IN. [NEW SOVIET DRUGS, AMMIFURIN AND BEROXAN, FOR THE TREATMENT OF ALOPECIA AREATA AND VITILIGO]. Vestn Dermatol Venerol. 1963 Oct;37:10-4. Russian. PubMed PMID: 14130948. 3: Karagezian LA, Rostomian RB, Bagdasarova ZhG. [Treatment of vitiligo with ammifurin, beroxan and ultraviolet rays]. Vestn Dermatol Venerol. 1978 Nov;(11):64-6. Russian. PubMed PMID: 735345. 4: Mordovtsev VN, Langner A, Timoshin GG, Wolska H, Kirsanova MM. [Local PUVA therapy of patients with psoriasis]. Vestn Dermatol Venerol. 1989;(1):69-71. Russian. PubMed PMID: 2718622. 5: Pisarenko MF, Kaukhova OIa, Shablinskaia EM, Karagioz GI, Lopukhova GM. [PUVA therapy in chronic dermatoses using a domestic photosensitizer]. Vestn Dermatol Venerol. 1983 Sep;(9):52-5. Russian. PubMed PMID: 6649871. 6: Hoffmann JS, Moustacchi E, Villani G, Sage E. In vitro DNA synthesis by DNA polymerase I and DNA polymerase alpha on single-stranded DNA containing either purine or pyrimidine monoadducts. Biochem Pharmacol. 1992 Sep 25;44(6):1123-9. PubMed PMID: 1417935.