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MedKoo Cat#: 563667 | Name: SJP-L-5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SJP-L-5 is a inhibitor of HIV-1 infection by blocking viral DNA nuclear entry.

Chemical Structure

SJP-L-5
SJP-L-5
CAS#1286237-83-9

Theoretical Analysis

MedKoo Cat#: 563667

Name: SJP-L-5

CAS#: 1286237-83-9

Chemical Formula: C18H19NO5

Exact Mass: 329.1263

Molecular Weight: 329.35

Elemental Analysis: C, 65.64; H, 5.82; N, 4.25; O, 24.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
SJP-L-5; SJP L 5; SJPL5;
IUPAC/Chemical Name
Methyl 6-[4-(dimethylamino)phenyl]-7-methoxy-1,3-benzodioxole-5-carboxylate
InChi Key
BVAOVMDHWBCWPH-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19NO5/c1-19(2)12-7-5-11(6-8-12)15-13(18(20)22-4)9-14-16(17(15)21-3)24-10-23-14/h5-9H,10H2,1-4H3
SMILES Code
O=C(C1=C(C2=CC=C(N(C)C)C=C2)C(OC)=C(OCO3)C3=C1)OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 329.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang XJ, Wang RR, Chen H, Luo RH, Yang LM, Liu JP, Sun HD, Zhang HB, Xiao WL, Zheng YT. SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure. Sci Rep. 2018 Feb 7;8(1):2574. doi: 10.1038/s41598-018-20954-5. PubMed PMID: 29416083; PubMed Central PMCID: PMC5803243. 2: Bai R, Zhang XJ, Li YL, Liu JP, Zhang HB, Xiao WL, Pu JX, Sun HD, Zheng YT, Liu LX. SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry. BMC Microbiol. 2015 Dec 2;15:274. doi: 10.1186/s12866-015-0605-3. PubMed PMID: 26630969; PubMed Central PMCID: PMC4667461.