LASSBio-1829 HCl | CAS#1807810-16-7 | IKK2 inhibitor

MedKoo Cat#: 563664 | Name: LASSBio-1829 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LASSBio-1829 HCl is an orally active IKK2 inhibitor.

Chemical Structure

LASSBio-1829 HCl

CAS#1807810-16-7

Theoretical Analysis

MedKoo Cat#: 563664

Name: LASSBio-1829 HCl

CAS#: 1807810-16-7

Chemical Formula: C25H19ClN4O

Exact Mass: 426.1247

Molecular Weight: 426.90

Elemental Analysis: C, 70.34; H, 4.49; Cl, 8.30; N, 13.12; O, 3.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LASSBio-1829 hydrochloride; LASSBio-1829 HCl; LASSBio 1829 HCl; LASSBio1829 HCl;

IUPAC/Chemical Name

Naphthalene-2-carboxylic acid [4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-benzylidene]-hydrazide Hydrochloride

InChi Key

RRNUQYVGPLOFKS-HRRMWDOSSA-N

InChi Code

InChI=1S/C25H18N4O.ClH/c30-25(21-10-9-18-3-1-2-4-20(18)15-21)29-28-16-17-5-7-19(8-6-17)22-11-13-26-24-23(22)12-14-27-24;/h1-16H,(H,26,27)(H,29,30);1H/b28-16+;

SMILES Code

O=C(C1=CC=C2C=CC=CC2=C1)N/N=C/C3=CC=C(C4=C5C(NC=C5)=NC=C4)C=C3.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 426.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Guedes IA, Freitas RH, Cordeiro NM, do Nascimento TS, Valerio TS, Fernandes PD, Dardenne LE, Fraga CA. LASSBio-1829 Hydrochloride: Development of a New Orally Active N-Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties. ChemMedChem. 2016 Jan 19;11(2):234-44. doi: 10.1002/cmdc.201500266. Epub 2015 Aug 25. PubMed PMID: 26306006.