MedKoo Cat#: 563655 | Name: Neurodazine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Neurodazine is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.

Chemical Structure

Neurodazine
Neurodazine
CAS#937807-66-4

Theoretical Analysis

MedKoo Cat#: 563655

Name: Neurodazine

CAS#: 937807-66-4

Chemical Formula: C27H21ClN2O3

Exact Mass: 456.1241

Molecular Weight: 456.92

Elemental Analysis: C, 70.97; H, 4.63; Cl, 7.76; N, 6.13; O, 10.50

Price and Availability

Size Price Availability Quantity
5mg USD 280.00
10mg USD 420.00
25mg USD 730.00
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Related CAS #
No Data
Synonym
Neurodazine;
IUPAC/Chemical Name
2-[5-(3-Chloro-phenyl)-furan-2-yl]-4,5-bis-(4-methoxy-phenyl)-1H-imidazole
InChi Key
FEEOFPAEDSMOTO-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)
SMILES Code
COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(C4=CC=C(C5=CC=CC(Cl)=C5)O4)N2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 456.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Halder D, Kim GH, Shin I. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37. doi: 10.1039/c5mb00161g. PubMed PMID: 25872738. 2: Pérez-Caaveiro C, Pérez Sestelo J, Martínez MM, Sarandeses LA. Triorganoindium reagents in selective palladium-catalyzed cross-coupling with iodoimidazoles: synthesis of neurodazine. J Org Chem. 2014 Oct 17;79(20):9586-93. doi: 10.1021/jo501664p. Epub 2014 Oct 1. PubMed PMID: 25203769. 3: Kim GH, Halder D, Park J, Namkung W, Shin I. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. doi: 10.1002/anie.201404871. Epub 2014 Jul 9. PubMed PMID: 25044422.