Pyridafenthion | CAS#119-12-0 | Organothiophosphate pesticide

MedKoo Cat#: 592796 | Name: Pyridafenthion

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyridiphenthion (also known as Pyridaphenthion) is dialkyl pyridazinonyl thiophosphate derivative. Pyridiphenthion acts as broad-spectrum insecticide and acaricide used in the control of sucking and chewing insects and spider mites in cereals, vegetables, fruits and ornamental crops.

Chemical Structure

Pyridafenthion

CAS#119-12-0

Theoretical Analysis

MedKoo Cat#: 592796

Name: Pyridafenthion

CAS#: 119-12-0

Chemical Formula: C14H17N2O4PS

Exact Mass: 340.0647

Molecular Weight: 340.33

Elemental Analysis: C, 49.41; H, 5.04; N, 8.23; O, 18.80; P, 9.10; S, 9.42

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Synonym

Pyridafenthion; Pyridiphenthion; Pyridaphenthion; Ofunack;

IUPAC/Chemical Name

O,O-Diethyl O-(1,6-dihydro-6-oxo-1-phenylpyridazin-3-yl) thiophosphate

InChi Key

CXJSOEPQXUCJSA-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H17N2O4PS/c1-3-18-21(22,19-4-2)20-13-10-11-14(17)16(15-13)12-8-6-5-7-9-12/h5-11H,3-4H2,1-2H3

SMILES Code

S=P(OCC)(OCC)OC(C=C1)=NN(C2=CC=CC=C2)C1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sampedro MC, Gomez de Balugera Z, Goicolea A, Barrio RJ. Determination of the insecticide pyridafenthion in river water, soils and wine by adsorptive stripping voltammetry. Food Addit Contam. 1998 Oct;15(7):793-800. PubMed PMID: 10211187. 2: Tomita M, Someya N, Sakama H, Nishimura M. [Determination of organic phosphorus in the blood. (2). Inhalation toxicity of pyridafenthion in rats]. Nihon Eiseigaku Zasshi. 1975 Apr;30(1):122. Japanese. PubMed PMID: 1169468. 3: Jokanović M, Maksimović M. A comparison of trimedoxime, obidoxime, pralidoxime and HI-6 in the treatment of oral organophosphorus insecticide poisoning in the rat. Arch Toxicol. 1995;70(2):119-23. PubMed PMID: 8773184. 4: Sabater C, Carrasco JM. Effects of pyridaphenthion on growth of five freshwater species of phytoplankton. A laboratory study. Chemosphere. 2001 Sep;44(8):1775-81. PubMed PMID: 11534908. 5: Sampedro MC, Martín O, López de Armentia CL, Goicolea, Rodríguez E, Gómez de Balugera ZG, Costa-Moreira J, Barrio RJ. Solid-phase microextraction for the determination of systemic and non-volatile pesticides in river water using gas chromatography with nitrogen-phosphorous and electron-capture detection. J Chromatogr A. 2000 Oct 6;893(2):347-58. PubMed PMID: 11073303. 6: Kotelenets AI, Kremko LM, Levoshchuk NP, Lukashevich NA, Aleksashina ZA. [Substantiation of hygienic standardization of ofunak in reservoir water]. Gig Sanit. 1988 Nov;(11):66-8. Russian. PubMed PMID: 2977362. 7: Buslovich SIu, Kotelenets AI. [Effect of ofunack on the tentative exploratory activity of white rats]. Gig Sanit. 1987 Aug;(8):80-2. Russian. PubMed PMID: 3692232. 8: García AM, Sabater MC, Mendoza MT, Ballester F, Carrasco JM. Exposure to organophosphate pesticides in a general population living in a rice growing area: an exploratory study. Bull Environ Contam Toxicol. 2000 Dec;65(6):764-71. PubMed PMID: 11080357. 9: Kotelenets AI, Buslovich SIu. [Evaluation of changes in memory and learning processes caused by pesticide poisoning]. Gig Sanit. 1991 Jul;(7):63-5. Russian. PubMed PMID: 1916374. 10: Lacorte S, Barceló D. Determination of organophosphorus pesticides and their transformation products in river waters by automated on-line solid-phase extraction followed by thermospray liquid chromatography-mass spectrometry. J Chromatogr A. 1995 Sep 29;712(1):103-12. PubMed PMID: 8556144. 11: Balança G, de Visscher M. Impacts on nontarget insects of a new insecticide compound used against the desert locust [Schistocerca gregaria (Forskål 1775)]. Arch Environ Contam Toxicol. 1997 Jan;32(1):58-62. PubMed PMID: 9002435. 12: Jonsson CM, Paraiba LC, Mendoza MT, Sabater C, Carrasco JM. Bioconcentration of the insecticide pyridaphenthion by the green algae Chlorella saccharophila. Chemosphere. 2001 Apr;43(3):321-5. PubMed PMID: 11302577. 13: Yamanaka S, Nishimura M. [Effects of organophosphorus compounds and PAM on cholinesterase activity in rat tissues]. Nihon Eiseigaku Zasshi. 1984 Dec;39(5):795-806. Japanese. PubMed PMID: 6533340. 14: Takahashi Y, Houjyo T, Kohjimoto T, Takagi Y, Mori K, Muraoka T, Annoh H, Ogiyama K, Funaki Y, Tanaka K, Wada Y, Fujita T. Impact of pretilachlor herbicide and pyridaphenthion insecticide on aquatic organisms in model streams. Ecotoxicol Environ Saf. 2007 Jun;67(2):227-39. Epub 2006 Aug 4. PubMed PMID: 16890290.