Mutalomycin | CAS#62618-08-0 | polyether antibiotic

MedKoo Cat#: 599194 | Name: Mutalomycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mutalomycin is a new metal-complexing polyether antibiotic produced by a strain of Streptomyces mutabilis NRRL 8088.

Chemical Structure

Mutalomycin

CAS#62618-08-0

Theoretical Analysis

MedKoo Cat#: 599194

Name: Mutalomycin

CAS#: 62618-08-0

Chemical Formula: C41H70O12

Exact Mass: 754.4867

Molecular Weight: 754.99

Elemental Analysis: C, 65.23; H, 9.35; O, 25.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Mutalomycin;

IUPAC/Chemical Name

(R)-2-((2R,3S,4S,5S,6S)-2-hydroxy-6-((R)-1-((2R,5R,7S,8R,9R)-9-hydroxy-2-((2R,2'S,3'R,5S,5'R)-5'-((2S,3R,5S,6R)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)ethyl)-4-methoxy-3,5-dimethyltetrahydro-2H-pyran-2-yl)propanoic acid

InChi Key

WWEDNBWYGGJQOV-AXJZMLAASA-N

InChi Code

InChI=1S/C41H70O12/c1-20-17-22(3)39(11,45)50-31(20)29-18-21(2)35(48-29)38(10)14-13-30(49-38)37(9)15-16-40(53-37)19-28(42)23(4)32(51-40)24(5)33-25(6)34(47-12)26(7)41(46,52-33)27(8)36(43)44/h20-35,42,45-46H,13-19H2,1-12H3,(H,43,44)/t20-,21-,22+,23-,24+,25-,26+,27+,28-,29-,30+,31+,32+,33-,34+,35+,37-,38-,39-,40-,41-/m1/s1

SMILES Code

O[C@H](C1)[C@@H](C)[C@@H]([C@H](C)[C@@H]2[C@H]([C@H](OC)[C@H](C)[C@@](O)(O2)[C@H](C(O)=O)C)C)O[C@@]31O[C@]([C@@H]4CC[C@@]([C@@H]5[C@H](C)C[C@H]([C@@H]6[C@H](C)C[C@H](C)[C@@](O)(C)O6)O5)(C)O4)(C)CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 754.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fehr T, Kuhn M, Loosli HR, Ponelle M, Boelsterli JJ, Walkinshaw MD. 2-Epimutalomycin and 28-epimutalomycin, two new polyether antibiotics from Streptomyces mutabilis. Derivatization of mutalomycin and the structure elucidation of two minor metabolites. J Antibiot (Tokyo). 1989 Jun;42(6):897-902. PubMed PMID: 2737949. 2: Fehr T, King HD, Kuhn M. Mutalomycin, a new polyether antibiotic taxonomy, fermentation, isolation and characterization. J Antibiot (Tokyo). 1977 Nov;30(11):903-7. PubMed PMID: 591458. 3: Seto H, Mizoue K, Otake N. Studies on the ionophorous antibiotics. XXVI. The assignments of the 13C-NMR spectra of lonomycin A and mutalomycin. J Antibiot (Tokyo). 1980 Sep;33(9):979-88. PubMed PMID: 7440419. 4: Fehr F, Keller-Juslén C, King HD, Loosli HR, Kuhn M, Von Wartburg A. Correction of the stereo structures of mutalomycin, noboritomycin A and noboritomycin B. J Antibiot (Tokyo). 1979 May;32(5):535-6. PubMed PMID: 528398.