Azidocillin sodium salt | CAS#35334-12-4 | penicillin

MedKoo Cat#: 599184 | Name: Azidocillin sodium salt

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azidocillin sodium salt is a type of penicillin.

Chemical Structure

Azidocillin sodium salt

CAS#35334-12-4

Theoretical Analysis

MedKoo Cat#: 599184

Name: Azidocillin sodium salt

CAS#: 35334-12-4

Chemical Formula: C16H16N5NaO4S

Exact Mass: 397.0821

Molecular Weight: 397.38

Elemental Analysis: C, 48.36; H, 4.06; N, 17.62; Na, 5.79; O, 16.10; S, 8.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Azidocillin sodium salt; Globacillin; Nalpen; Longatren;

IUPAC/Chemical Name

sodium (2R,5S,6S)-6-(2-azido-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChi Key

DKUPMJBOYNDXNY-BQQXAYLNSA-M

InChi Code

InChI=1S/C16H17N5O4S.Na/c1-16(2)11(15(24)25)21-13(23)10(14(21)26-16)18-12(22)9(19-20-17)8-6-4-3-5-7-8;/h3-7,9-11,14H,1-2H3,(H,18,22)(H,24,25);/q;+1/p-1/t9?,10-,11+,14-;/m0./s1

SMILES Code

O=C([C@H](C(C)(C)S[C@@]1([H])[C@H]2NC(C(N=[N+]=[N-])C3=CC=CC=C3)=O)N1C2=O)[O-].[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 397.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Płotkowiak Z, Popielarz-Brzezińska M, Serafin M. Methods for the assessment of quality and stability of azidocillin. Acta Pol Pharm. 2003 Mar-Apr;60(2):112-5. PubMed PMID: 13678317. 2: Bystedt H, von Konow L, Nord CE. A comparison of the effect of phenoxymethylpenicillin and azidocillin on postoperative complications after surgical removal of impacted mandibular third molars. Swed Dent J. 1981;5(5-6):225-34. PubMed PMID: 6800046. 3: Axelsson A, Jensen C, Melin O, Singer F, von Sydow C. Treatment of acute maxillary sinusitis. V. Amoxicillin azidocillin, phenylpropanolamine and pivampicillin. Acta Otolaryngol. 1981 Mar-Apr;91(3-4):313-8. PubMed PMID: 6894819. 4: Gonschewski HH, Stempel G. [Treatment of chronic bronchitis with azidocillin and co-trimoxazole]. Fortschr Med. 1981 Mar 12;99(10):357-60. German. PubMed PMID: 6971244. 5: Wieser O, Weuta H. Azidocillin in acute attacks of chronic bronchitis. Comparisons of b.i.d. and t.i.d. administration. Br J Clin Pract. 1980 Apr;34(4):101-6. PubMed PMID: 6893157. 6: Margarit F, Moreno-Dalmau J, Obach R, Peraire C, Plá-Delfina JM. Intestinal absorption kinetics of a series of aminopenicillins and azidocillin. A comparative study in the rat. Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:102-7. PubMed PMID: 1820862. 7: Bystedt H, Nord CE, Nordenram A. Effect of azidocillin, erythromycin, clindamycin and doxycycline on postoperative complications after surgical removal of impacted mandibular third molars. Int J Oral Surg. 1980 Jun;9(3):157-65. PubMed PMID: 6777314. 8: Bergan T, Sørensen G. Pharmacokinetics of azidocillin in healthy adults. Arzneimittelforschung. 1980;30(12):2185-91. PubMed PMID: 6894241. 9: Schildwächter G. [Azidocillin in chronic bronchitis. A comparative study with SMZ/TMP]. Med Welt. 1977 Jan 28;28(4):190-3. German. PubMed PMID: 576491. 10: Lauriello G, Perillo G, Novarese AM, Calvanese RC, Giustiniani B, Capuano L, Violante L. [Clinical experience with azidocillin in pneumonology and otorhinolaryngology]. G Ital Chemioter. 1980 Jan-Jun;27(1):7-14. Italian. PubMed PMID: 6895200. 11: Bystedt H, DAhlbäck A, Dornbusch K, Nord CE. Concentrations of azidocillin, erythromycin, doxycycline and clindamycin in human mandibular bone. Int J Oral Surg. 1978 Oct;7(5):442-9. PubMed PMID: 102599. 12: Wieser O, Weuta H. [Oral treatment of the acute attack in chronic bronchitis. Comparison of azidocillin and amoxicillin]. Med Welt. 1982 May 28;33(21):794-6. German. PubMed PMID: 6896550. 13: Stejskal VD, Forsbeck M, Olin R. Side-chain-specific lymphocyte responses in workers with occupational allergy induced by penicillins. Int Arch Allergy Appl Immunol. 1987;82(3-4):461-4. PubMed PMID: 3570513. 14: Ryrfeldt A, Bodin NO, Hansson E. Biliary excretion of ampicillin, azidocillin and benzylpenicillin in the rat. Acta Pharmacol Toxicol (Copenh). 1973;33(3):219-28. PubMed PMID: 4800784. 15: Bergamini A, Vivarelli R, Gualtieri R, Vandelli MR. [Clinical use of azidocillin in chronic bronchopneumopathy in the aged re-manifesting acutely]. G Ital Chemioter. 1980 Jul-Dec;27(2):91-6. Italian. PubMed PMID: 6896192. 16: Wasz-Höckert O, Nummi S, Vuopala S, Järvinen PA. Transplacental passage of azidocillin, ampicillin and penicillin G during early and late pregnancy. Acta Paediatr Scand Suppl. 1970;206:Suppl 206:109+. PubMed PMID: 5276929. 17: Wasz-Höckert O, Nummi S, Vuopala S, Järvinen PA. Transplacental passage of azidocillin, ampicillin and penicillin G during early and late pregnancy. Scand J Infect Dis. 1970;2(2):125-30. PubMed PMID: 4329175. 18: Bystedt H, Dahlbäck A, Nord CE. Concentration of azidocillin, erythromycin, doxycycline and clindamycin in dental alveolar serum after single oral doses. Int J Oral Surg. 1977 Apr;6(2):65-74. PubMed PMID: 405337. 19: Barbato G, Cavalieri S, Salerno A. [Clinical use of azidocillin in pediatrics. Evaluation of the clinical effectiveness and tolerance in respiratory and otorhinolaryngologic infections]. Minerva Pediatr. 1982 May 31;34(10):469-74. Italian. PubMed PMID: 6897099. 20: Mignone F, Sardella ML, Leone N, Sciolla N, Vianzone M, Bona F, Ciravegna P, Martina A. [Azidocillin and streptococcal infections: pharmacokinetics and clinical aspects]. Minerva Pediatr. 1983 Jun 15;35(11):587-95. Italian. PubMed PMID: 6688654.