Senegalensin | CAS#68236-11-3 | isoflavoneisoflavone

MedKoo Cat#: 599176 | Name: Senegalensin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Senegalensin is an isoflavone isolated from stem bark of Cameroonian medicinal plant Erythrina senegalensis.

Chemical Structure

Senegalensin

CAS#68236-11-3

Theoretical Analysis

MedKoo Cat#: 599176

Name: Senegalensin

CAS#: 68236-11-3

Chemical Formula: C25H28O5

Exact Mass: 408.1937

Molecular Weight: 408.49

Elemental Analysis: C, 73.51; H, 6.91; O, 19.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Senegalensin; Lonchocarpol A;

IUPAC/Chemical Name

(S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-en-1-yl)chroman-4-one

InChi Key

HCNLDGTUMBOHKT-NRFANRHFSA-N

InChi Code

InChI=1S/C25H28O5/c1-14(2)5-11-18-23(28)19(12-6-15(3)4)25-22(24(18)29)20(27)13-21(30-25)16-7-9-17(26)10-8-16/h5-10,21,26,28-29H,11-13H2,1-4H3/t21-/m0/s1

SMILES Code

O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=C(C/C=C(C)\C)C(O)=C(C/C=C(C)\C)C(O)=C13

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 408.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanaka H, Doi M, Etoh H, Watanabe N, Shimizu H, Hirata M, Ahmad M, Qurashi I, Khan MR. Revised structures for senegalensin and euchrenone b(10). J Nat Prod. 2001 Oct;64(10):1336-40. PubMed PMID: 11678662. 2: Wandji J, Nkengfack AE, Fomum ZT, Ubillas R, Killday KB, Tempesta MS. A new prenylated isoflavone and long chain esters from two Erythrina species. J Nat Prod. 1990 Nov-Dec;53(6):1425-9. PubMed PMID: 2089116. 3: Nkengfack AE, Meyer M, Tempesta MS, Fomum ZT. Auriculatin 4'-O-Glucoside: A New Prenylated Isoflavone Glycoside from Erythrina eriotricha1. Planta Med. 1991 Oct;57(5):488-91. PubMed PMID: 17226186. 4: Wandji J, Fomum ZT, Tillequin F, Skaltsounis AL, Koch M. Erysenegalenseins H and I: Two New Isoflavones from Erythrina senegalensis1. Planta Med. 1994 Apr;60(2):178-80. PubMed PMID: 17236036. 5: Khaomek P, Ichino C, Ishiyama A, Sekiguchi H, Namatame M, Ruangrungsi N, Saifah E, Kiyohara H, Otoguro K, Omura S, Yamada H. In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca. J Nat Med. 2008 Apr;62(2):217-20. doi: 10.1007/s11418-007-0214-z. Epub 2008 Jan 30. PubMed PMID: 18404327. 6: Bae EY, Na M, Njamen D, Mbafor JT, Fomum ZT, Cui L, Choung DH, Kim BY, Oh WK, Ahn JS. Inhibition of protein tyrosine phosphatase 1B by prenylated isoflavonoids isolated from the stem bark of Erythrina addisoniae. Planta Med. 2006 Aug;72(10):945-8. PubMed PMID: 16972201. 7: Salvatore MJ, King AB, Graham AC, Onishi HR, Bartizal KF, Abruzzo GK, Gill CJ, Ramjit HG, Pitzenberger SM, Witherup KM. Antibacterial activity of lonchocarpol A. J Nat Prod. 1998 May;61(5):640-2. PubMed PMID: 9599265.