Lofenal | CAS#10047-08-2 | cytostatic drug

MedKoo Cat#: 599155 | Name: Lofenal

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lofenal is a cytostatic drug.

Chemical Structure

Lofenal

CAS#10047-08-2

Theoretical Analysis

MedKoo Cat#: 599155

Name: Lofenal

CAS#: 10047-08-2

Chemical Formula: C21H24Cl2N2O3

Exact Mass: 422.1164

Molecular Weight: 423.33

Elemental Analysis: C, 59.58; H, 5.71; Cl, 16.75; N, 6.62; O, 11.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lofenal;

IUPAC/Chemical Name

(2-(4-(bis(2-chloroethyl)amino)phenyl)acetyl)phenylalanine

InChi Key

WOJORPYBSQEBBK-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H24Cl2N2O3/c22-10-12-25(13-11-23)18-8-6-17(7-9-18)15-20(26)24-19(21(27)28)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2,(H,24,26)(H,27,28)

SMILES Code

O=C(O)C(CC1=CC=CC=C1)NC(CC2=CC=C(N(CCCl)CCCl)C=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 423.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Breĭvis PV, Gar'kavyĭ MI. [Clinico-biochemical aspects of the polychemotherapy of disseminated lymphogranulomatosis resistant to the COPP protocol]. Antibiot Med Biotekhnol. 1986 Jan;31(1):52-5. Russian. PubMed PMID: 3753837. 2: Pavilonis SV, Zhukene IaV, Didzhiapetrene IaK, Grazhialene GIu. [Effect of lofenal on rat embryogenesis]. Eksp Onkol. 1984;6(3):66-9. Russian. PubMed PMID: 6499744. 3: [New drug preparations: polyglucin, hemodes, lofenal]. Farmatsiia. 1972 Sep-Oct;21(5):88-94. Russian. PubMed PMID: 4662707.