Harman (1-methyl-β-carboline) is a naturally occurring β-carboline alkaloid that acts as a monoamine oxidase A (MAO-A) inhibitor, modulating neurotransmitter metabolism. It exhibits neuroactive and psychoactive properties, with potential implications in treating neurodegenerative diseases and mood disorders by increasing dopamine and serotonin levels. Additionally, harman has shown cytotoxic and antiproliferative effects through interaction with topoisomerase enzymes, making it a potential candidate for anticancer drug development.
MedKoo Cat#: 599132
Name: Harman
CAS#: 486-84-0
Chemical Formula: C12H10N2
Exact Mass: 182.0844
Molecular Weight: 182.22
Elemental Analysis: C, 79.10; H, 5.53; N, 15.37
The following data is based on the product molecular weight 182.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
