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MedKoo Cat#: 563619 | Name: 5-AcTMF

Description:

WARNING: This product is for research use only, not for human or veterinary use.

5-AcTMF is an inducer of G2/M arrest, apoptosis and autophagy in cancer cells.

Chemical Structure

5-AcTMF
5-AcTMF
CAS#1620970-95-7

Theoretical Analysis

MedKoo Cat#: 563619

Name: 5-AcTMF

CAS#: 1620970-95-7

Chemical Formula: C21H20O8

Exact Mass: 400.1158

Molecular Weight: 400.38

Elemental Analysis: C, 63.00; H, 5.04; O, 31.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
5-AcTMF; 5 AcTMF; 5AcTMF; 5-ATMF; 5-ATAN; 5 ATMF; 5 ATAN; 5ATMF; 5ATAN;
IUPAC/Chemical Name
6,7,8-trimethoxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-5-yl acetate
InChi Key
YDUCEDBMSYZHAA-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H20O8/c1-11(22)28-17-16-14(23)10-15(12-6-8-13(24-2)9-7-12)29-18(16)20(26-4)21(27-5)19(17)25-3/h6-10H,1-5H3
SMILES Code
O=C1C=C(C2=CC=C(OC)C=C2)OC3=C1C(OC(C)=O)=C(OC)C(OC)=C3OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 400.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li YR, Li S, Ho CT, Chang YH, Tan KT, Chung TW, Wang BY, Chen YK, Lin CC. Tangeretin derivative, 5-acetyloxy-6,7,8,4'-tetramethoxyflavone induces G2/M arrest, apoptosis and autophagy in human non-small cell lung cancer cells in vitro and in vivo. Cancer Biol Ther. 2016;17(1):48-64. doi: 10.1080/15384047.2015.1108491. PubMed PMID: 26569090; PubMed Central PMCID: PMC4847812.