MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 599061 | Name: Trepirium iodide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Trepirium iodide is a Ganglioblokator.

Chemical Structure

Trepirium iodide
Trepirium iodide
CAS#1018-34-4

Theoretical Analysis

MedKoo Cat#: 599061

Name: Trepirium iodide

CAS#: 1018-34-4

Chemical Formula: C12H26I2N2O2

Exact Mass:

Molecular Weight: 484.16

Elemental Analysis: C, 29.77; H, 5.41; I, 52.42; N, 5.79; O, 6.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Trepirium iodide; LL-1; LL 1; LL1; Iodure de trepirium; Hygronium; Hygronii;
IUPAC/Chemical Name
1,1-dimethyl-2-((2-(trimethylammonio)ethoxy)carbonyl)pyrrolidin-1-ium iodide
InChi Key
CODSEWNHIHYVHK-UHFFFAOYSA-L
InChi Code
InChI=1S/C12H26N2O2.2HI/c1-13(2,3)9-10-16-12(15)11-7-6-8-14(11,4)5;;/h11H,6-10H2,1-5H3;2*1H/q+2;;/p-2
SMILES Code
O=C(C1[N+](C)(C)CCC1)OCC[N+](C)(C)C.[I-].[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 484.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ryszka F, Dolińska B, Zieliński M, Chyra D, Dobrzański Z. Permeation of iodide from iodine-enriched yeast through porcine intestine. Acta Biochim Pol. 2013;60(4):737-9. Epub 2013 Dec 20. PubMed PMID: 24364046. 2: Iwata A, Morrison ML, Roth MB. Iodide protects heart tissue from reperfusion injury. PLoS One. 2014 Nov 7;9(11):e112458. doi: 10.1371/journal.pone.0112458. eCollection 2014. Erratum in: PLoS One. 2015;10(9):e0138396. PubMed PMID: 25379708; PubMed Central PMCID: PMC4224479. 3: Shiroyama K, Kawasaki Y, Unno Y, Amachi S. A putative multicopper oxidase, IoxA, is involved in iodide oxidation by Roseovarius sp. strain A-2. Biosci Biotechnol Biochem. 2015;79(11):1898-905. doi: 10.1080/09168451.2015.1052767. Epub 2015 Jun 4. PubMed PMID: 26041311. 4: Dielacher B, Tiefenauer RF, Junesch J, Vörös J. Iodide sensing via electrochemical etching of ultrathin gold films. Nanotechnology. 2015 Jan 16;26(2):025202. doi: 10.1088/0957-4484/26/2/025202. Epub 2014 Dec 16. PubMed PMID: 25513753. 5: Kong F, Meng X, Chu R, Xu K, Tang B. A turn-on fluorescence probe for imaging iodide in living cells based on an elimination reaction. Chem Commun (Camb). 2015 Apr 25;51(32):6925-7. doi: 10.1039/c5cc01130b. Epub 2015 Mar 20. PubMed PMID: 25794327. 6: Michalke B, Witte H. Characterization of a rapid and reliable method for iodide biomonitoring in serum and urine based on ion chromatography-ICP-mass spectrometry. J Trace Elem Med Biol. 2015 Jan;29:63-8. doi: 10.1016/j.jtemb.2014.05.002. Epub 2014 May 21. PubMed PMID: 24933092. 7: Yang Y, Komaki Y, Kimura SY, Hu HY, Wagner ED, Mariñas BJ, Plewa MJ. Toxic impact of bromide and iodide on drinking water disinfected with chlorine or chloramines. Environ Sci Technol. 2014 Oct 21;48(20):12362-9. doi: 10.1021/es503621e. Epub 2014 Oct 7. PubMed PMID: 25222908. 8: Kaur A, Raj T, Kaur S, Singh N, Kaur N. Fluorescent organic nanoparticles of dihydropyrimidone derivatives for selective recognition of iodide using a displacement assay: application of the sensors in water and biological fluids. Org Biomol Chem. 2015 Jan 28;13(4):1204-12. doi: 10.1039/c4ob02152e. Epub 2014 Nov 27. PubMed PMID: 25428514. 9: Lumen A, Mattie DR, Fisher JW. Evaluation of perturbations in serum thyroid hormones during human pregnancy due to dietary iodide and perchlorate exposure using a biologically based dose-response model. Toxicol Sci. 2013 Jun;133(2):320-41. doi: 10.1093/toxsci/kft078. Epub 2013 Mar 27. PubMed PMID: 23535361. 10: Zhang Y, Dai T, Wang M, Vecchio D, Chiang LY, Hamblin MR. Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies. Nanomedicine (Lond). 2015 Mar;10(4):603-14. doi: 10.2217/nnm.14.131. PubMed PMID: 25723093; PubMed Central PMCID: PMC4899971. 11: Shakila K, Kalainathan S. Synthesis aspects, structural, spectroscopic, antimicrobial and room temperature ferromagnetism of zinc iodide complex with Schiff based ligand. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jan 25;135:1059-65. doi: 10.1016/j.saa.2014.08.006. Epub 2014 Aug 12. PubMed PMID: 25173522. 12: Alayoubi A, Sullivan RD, Lou H, Patel H, Mandrell T, Helms R, Almoazen H. In Vivo Evaluation of Transdermal Iodide Microemulsion for Treating Iodine Deficiency Using Sprague Dawley Rats. AAPS PharmSciTech. 2016 Jun;17(3):618-30. doi: 10.1208/s12249-015-0392-z. Epub 2015 Aug 20. PubMed PMID: 26288943. 13: Sandhu S, Kumar R, Singh P, Walia A, Vanita V, Kumar S. Ratiometric fluorophore for quantification of iodide under physiological conditions: applications in urine analysis and live cell imaging. Org Biomol Chem. 2016 Apr 14;14(14):3536-43. doi: 10.1039/c6ob00373g. Epub 2016 Mar 15. PubMed PMID: 26975579. 14: Frizzarin RM, Aguado E, Portugal LA, Moreno D, Estela JM, Rocha FR, Cerdà V. A portable multi-syringe flow system for spectrofluorimetric determination of iodide in seawater. Talanta. 2015 Nov 1;144:1155-62. doi: 10.1016/j.talanta.2015.07.069. Epub 2015 Jul 29. PubMed PMID: 26452941. 15: Chen XY, Lin CH, Yang LH, Li WG, Zhang JW, Zheng WW, Wang X, Qian J, Huang JL, Lei YX. The Effect on Sodium/Iodide Symporter and Pendrin in Thyroid Colloid Retention Developed by Excess Iodide Intake. Biol Trace Elem Res. 2016 Jul;172(1):193-200. doi: 10.1007/s12011-015-0580-4. Epub 2015 Dec 11. PubMed PMID: 26660892. 16: Lebedeva NSh, Malkova EA, Popova TE, Kutyrev AE, Syrbu SA, Parfenyuk EV, Vyugin AI. Interaction peculiarities of 5,10,15,20-tetrakis(4-N-methylpyridil) tetra iodide porphyrin with albumin. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 24;118:395-8. doi: 10.1016/j.saa.2013.06.101. Epub 2013 Jul 16. PubMed PMID: 24076455. 17: Zhang J, Xu X, Yang C, Yang F, Yang X. Colorimetric iodide recognition and sensing by citrate-stabilized core/shell Cu@Au nanoparticles. Anal Chem. 2011 May 15;83(10):3911-7. doi: 10.1021/ac200480r. Epub 2011 Apr 20. PubMed PMID: 21449559. 18: Solis-S JC, Villalobos P, Orozco A, Delgado G, Quintanar-Stephano A, Garcia-Solis P, Hernandez-Montiel HL, Robles-Osorio L, Valverde-R C. Inhibition of intrathyroidal dehalogenation by iodide. J Endocrinol. 2011 Jan;208(1):89-96. doi: 10.1677/JOE-10-0300. Epub 2010 Oct 25. PubMed PMID: 20974636. 19: Patil R, Tayade K, Sahoo SK, Singh J, Singh N, Hundiwale D, Kuwar A. Ratiometric fluorescent scaffold giving discrete response towards iodide ion: a combined experimental and DFT study. J Mol Recognit. 2014 Nov;27(11):683-8. doi: 10.1002/jmr.2392. PubMed PMID: 25277093. 20: Calil-Silveira J, Serrano-Nascimento C, Nunes MT. Iodide treatment acutely increases pendrin (SLC26A4) mRNA expression in the rat thyroid and the PCCl3 thyroid cell line by transcriptional mechanisms. Mol Cell Endocrinol. 2012 Mar 5;350(1):118-24. doi: 10.1016/j.mce.2011.12.002. Epub 2011 Dec 9. PubMed PMID: 22178794.

View History

Pelagiomicin A

Pelagiomicin A