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MedKoo Cat#: 461645 | Name: Imiprothrin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Imiprothrin is a fast-acting synthetic pyrethroid insecticide that targets the insect nervous system by modulating voltage-gated sodium channels, leading to prolonged depolarization, paralysis, and death. It is commonly used in aerosol formulations for indoor pest control due to its high efficacy at low concentrations and low mammalian toxicity. Despite its potent neurotoxicity in insects, imiprothrin exhibits relatively low environmental persistence and bioaccumulation potential.

Chemical Structure

Imiprothrin
Imiprothrin
CAS#72963-72-5

Theoretical Analysis

MedKoo Cat#: 461645

Name: Imiprothrin

CAS#: 72963-72-5

Chemical Formula: C17H22N2O4

Exact Mass: 318.1600

Molecular Weight: 318.37

Elemental Analysis: C, 64.13; H, 6.97; N, 8.80; O, 20.10

Price and Availability

Size Price Availability Quantity
50mg USD 1,200.00 2 Weeks
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Related CAS #
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Synonym
Imiprothrin; Pralle; Pralle T; S 4056F; S-4056F; S4056F; S-41311; S 41311; S41311;
IUPAC/Chemical Name
(2,5-dioxo-3-(prop-2-yn-1-yl)imidazolidin-1-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
InChi Key
VPRAQYXPZIFIOH-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H22N2O4/c1-6-7-18-9-13(20)19(16(18)22)10-23-15(21)14-12(8-11(2)3)17(14,4)5/h1,8,12,14H,7,9-10H2,2-5H3
SMILES Code
O=C(C1C(C)(C)C1/C=C(C)\C)OCN(C(N(CC#C)C2)=O)C2=O
Appearance
Solid powder
Purity
>98% (mixture of isomers)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Germant OM, Shashina NI. [EFFECT OF PYRETHROIDS ON TAIGA TICKS (IXODES PERSULCATUS IXODIDAE)]. Med Parazitol (Mosk). 2016 Jan-Mar;(1):60-2. Russian. PubMed PMID: 27029149. 2: Emara AM, Draz EI. Immunotoxicological study of one of the most common over-the-counter pyrethroid insecticide products in Egypt. Inhal Toxicol. 2007 Sep;19(12):997-1009. PubMed PMID: 17917914. 3: Fang F, Bernigaud C, Candy K, Melloul E, Izri A, Durand R, Botterel F, Chosidow O, Huang W, Guillot J. Efficacy assessment of biocides or repellents for the control of Sarcoptes scabiei in the environment. Parasit Vectors. 2015 Aug 12;8:416. doi: 10.1186/s13071-015-1027-7. PubMed PMID: 26259713; PubMed Central PMCID: PMC4531531. 4: Mir-Tutusaus JA, Masís-Mora M, Corcellas C, Eljarrat E, Barceló D, Sarrà M, Caminal G, Vicent T, Rodríguez-Rodríguez CE. Degradation of selected agrochemicals by the white rot fungus Trametes versicolor. Sci Total Environ. 2014 Dec 1;500-501:235-42. doi: 10.1016/j.scitotenv.2014.08.116. Epub 2014 Sep 15. PubMed PMID: 25217998. 5: Yan H, Qiao F, Tian M, Row KH. Simultaneous determination of nine pyrethroids in indoor insecticide products by capillary gas chromatography. J Pharm Biomed Anal. 2010 Feb 5;51(3):774-7. doi: 10.1016/j.jpba.2009.09.048. Epub 2009 Oct 7. PubMed PMID: 19875265. 6: Raeppel C, Appenzeller BM, Millet M. Determination of seven pyrethroids biocides and their synergist in indoor air by thermal-desorption gas chromatography/mass spectrometry after sampling on Tenax TA ® passive tubes. Talanta. 2015 Jan;131:309-14. doi: 10.1016/j.talanta.2014.07.098. Epub 2014 Aug 8. PubMed PMID: 25281107. 7: Ritchie SA, Buhagiar TS, Townsend M, Hoffmann A, Van Den Hurk AF, McMahon JL, Eiras AE. Field validation of the gravid Aedes trap (GAT) for collection of Aedes aegypti (Diptera: Culicidae). J Med Entomol. 2014 Jan;51(1):210-9. PubMed PMID: 24605471. 8: Ritchie SA, Montgomery BL, Walsh ID, Long SA, Hart AJ. Efficacy of an aerosol surface spray against container-breeding Aedes. J Am Mosq Control Assoc. 2001 Jun;17(2):147-9. PubMed PMID: 11480825. 9: Yoshida T. Simultaneous determination of 18 pyrethroids in indoor air by gas chromatography/mass spectrometry. J Chromatogr A. 2009 Jun 26;1216(26):5069-76. doi: 10.1016/j.chroma.2009.04.087. Epub 2009 May 3. PubMed PMID: 19457492. 10: Quirós-Alcalá L, Bradman A, Nishioka M, Harnly ME, Hubbard A, McKone TE, Ferber J, Eskenazi B. Pesticides in house dust from urban and farmworker households in California: an observational measurement study. Environ Health. 2011 Mar 16;10:19. doi: 10.1186/1476-069X-10-19. PubMed PMID: 21410986; PubMed Central PMCID: PMC3071308. 11: Adedeji AA, Ahmed IA, Akinwunmi M, Aina SA, Tikare O, Adeboye AF, Badmos SO, Adedeji KA, Fehintola FA, Amoo AO. Use and effectiveness of commercial flit-spray insecticides in control of mosquito population in Sagamu, Southwest Nigeria. Afr J Med Med Sci. 2012 Jun;41(2):197-203. PubMed PMID: 23185919. 12: Sumida K, Saito K, Ooe N, Isobe N, Kaneko H, Nakatsuka I. Evaluation of in vitro methods for detecting the effects of various chemicals on the human progesterone receptor, with a focus on pyrethroid insecticides. Toxicol Lett. 2001 Jan 3;118(3):147-55. PubMed PMID: 11137321. 13: Chansang U, Mulla MS. Control of aggregated populations of the eye fly Siphunculina funicola (diptera: chloropidae) using pyrethroid aerosols. Southeast Asian J Trop Med Public Health. 2008 Mar;39(2):246-51. PubMed PMID: 18564709. 14: Saito K, Tomigahara Y, Ohe N, Isobe N, Nakatsuka I, Kaneko H. Lack of significant estrogenic or antiestrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms. Toxicol Sci. 2000 Sep;57(1):54-60. PubMed PMID: 10966511. 15: Ramesh A, Ravi PE. Electron ionization gas chromatography-mass spectrometric determination of residues of thirteen pyrethroid insecticides in whole blood. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 5;802(2):371-6. PubMed PMID: 15018801. 16: Chedik L, Bruyere A, Le Vee M, Stieger B, Denizot C, Parmentier Y, Potin S, Fardel O. Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin. PLoS One. 2017 Jan 18;12(1):e0169480. doi: 10.1371/journal.pone.0169480. eCollection 2017. PubMed PMID: 28099443; PubMed Central PMCID: PMC5242521.