Stresson | CAS#29876-08-2 | bunitrolol

MedKoo Cat#: 558553 | Name: Stresson

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Stresson is a beta-blocking agent bunitrolol.

Chemical Structure

Stresson

CAS#29876-08-2

Theoretical Analysis

MedKoo Cat#: 558553

Name: Stresson

CAS#: 29876-08-2

Chemical Formula: C14H21ClN2O2

Exact Mass:

Molecular Weight: 284.78

Elemental Analysis: C, 59.05; H, 7.43; Cl, 12.45; N, 9.84; O, 11.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Stresson; Betriol; Koe 1366;

IUPAC/Chemical Name

(1)-2-(3-((tert-Butyl)amino)-2-hydroxypropoxy)benzonitrile monohydrochloride

InChi Key

RJPWESHPIMRNNM-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H20N2O2.ClH/c1-14(2,3)16-9-12(17)10-18-13-7-5-4-6-11(13)8-15;/h4-7,12,16-17H,9-10H2,1-3H3;1H

SMILES Code

N#CC1=CC=CC=C1OCC(O)CNC(C)(C)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 284.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Böhm H, Höhm B, Ludwig B, Madl W, Werner F. [Ergometric dose-effect study of bunitrolol (Stresson) in patients with coronary heart disease (author's transl)]. Wien Med Wochenschr. 1981 Sep 30;131(18):457-61. German. PubMed PMID: 6117988. 2: Hallay J, Kovács G, Szatmári K, Bakó A, Szentkereszty Z, Lakos G, Sipka S, Sápy P. Early jejunal nutrition and changes in the immunological parameters of patients with acute pancreatitis. Hepatogastroenterology. 2001 Sep-Oct;48(41):1488-92. PubMed PMID: 11677993. 3: Leodolter S, Müller-Tyl E, Philipp K, Salem G, Janisch H. [The influence of ritodrine-hcl (prepar), bunitrolol (stresson) and oxytocin (syntocinon) on Uteroplacental perfusion (author's transl)]. Z Geburtshilfe Perinatol. 1979 Apr;183(2):111-7. German. PubMed PMID: 35885. 4: Sarac F, Salman T, Gun F, Celik A, Gurler N, Dogru Abbasoglu S, Olgac V, Saygili A. Effect of probiotic supplementation on bacterial translocation in common bile duct obstruction. Pediatr Surg Int. 2015 Feb;31(2):155-61. doi: 10.1007/s00383-014-3643-2. Epub 2014 Dec 13. PubMed PMID: 25503581. 5: Grajek S, Szymczyńska A, Urbański K, Lehman Z, Kozłowska F, Paradowski S, Gracz M. [Viskaldix for treatment of patients with moderate arterial hypertension. Comparative estimation of hemodynamic changes during treatment with Viskaldix and Stresson]. Kardiol Pol. 1986;29(7):440-53. Polish. PubMed PMID: 2879953. 6: Hallay J, Kovács G, Bakó A, Kovács G, Szentkereszty Z, Mehrdad GB, Lakos G, Sipka S. [Jejunal feeding in necrotizing pancreatitis or after esophagectomy]. Magy Seb. 2002 Aug;55(4):272-7. Hungarian. PubMed PMID: 12236086. 7: Torche F. The effect of maternal stress on birth outcomes: exploiting a natural experiment. Demography. 2011 Nov;48(4):1473-91. doi: 10.1007/s13524-011-0054-z. PubMed PMID: 21870187. 8: Hallay J, Kovács G, Kiss Sz S, Farkas M, Lakos G, Sipka S, Bodolay E, Sápy P. Changes in the nutritional state and immune-serological parameters of esophagectomized patients fed jejunaly with glutamine-poor and glutamine-rich nutriments. Hepatogastroenterology. 2002 Nov-Dec;49(48):1555-9. PubMed PMID: 12397734. 9: Gun F, Salman T, Gurler N, Olgac V. Effect of probiotic supplementation on bacterial translocation in thermal injury. Surg Today. 2005;35(9):760-4. PubMed PMID: 16133671. 10: Pokrovskiĭ VM, Mingalev AN. [The regulatory-adaptive status in the evaluation of human stress-resistance]. Fiziol Cheloveka. 2012 Jan-Feb;38(1):77-81. Russian. PubMed PMID: 22567839. 11: [Stress causes stress--on the toilet]. Kinderkrankenschwester. 2005 Jan;24(1):20. German. PubMed PMID: 15712706. 12: Lobo DN, Williams RN, Welch NT, Aloysius MM, Nunes QM, Padmanabhan J, Crowe JR, Iftikhar SY, Parsons SL, Neal KR, Allison SP, Rowlands BJ. Early postoperative jejunostomy feeding with an immune modulating diet in patients undergoing resectional surgery for upper gastrointestinal cancer: a prospective, randomized, controlled, double-blind study. Clin Nutr. 2006 Oct;25(5):716-26. Epub 2006 Jun 13. PubMed PMID: 16777271. 13: Levander S, Gillner A. Metipranolol and propranolol: no CNS effects of a single oral dose. Psychopharmacology (Berl). 1982;76(4):359-66. PubMed PMID: 6126894. 14: Komaki I. [Experimental study on the bone reaction to mechanical stress--on the histochemical reaction of the bone and cartilage]. Nihon Seikeigeka Gakkai Zasshi. 1971 Sep;45(9):715-29. Japanese. PubMed PMID: 5168257. 15: Keul J, Lehmann M, Wybitul K. [Effect of bunitrolol on heart rate, metabolic parameters during physical exercise, and performance]. Arzneimittelforschung. 1981;31(11):1948-53. German. PubMed PMID: 6119096. 16: Smith RL, Carter DR, Schurman DJ. Pressure and shear differentially alter human articular chondrocyte metabolism: a review. Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S89-95. Review. PubMed PMID: 15480081. 17: Otto E, Gruner P, Weber H. [Periods and amplitude distribution parameters of the EEG in mental stress--on the concordance of mechanical and visuomanual methods of evaluation]. Psychiatr Neurol Med Psychol (Leipz). 1983 Dec;35(12):727-35. German. PubMed PMID: 6669655. 18: Touma M. Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System. J Vis Exp. 2018 May 5;(135). doi: 10.3791/57210. PubMed PMID: 29781990. 19: Maharjan R, Mukhopadhyay S, Allen B, Storz T, Brown E. Constitutive relation for the system-spanning dynamically jammed region in response to impact of cornstarch and water suspensions. Phys Rev E. 2018 May;97(5-1):052602. doi: 10.1103/PhysRevE.97.052602. PubMed PMID: 29906932.