MedKoo Cat#: 563582 | Name: Cilostamide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cilostamide is a selective inhibitor of type III phosphodiesterase (PDE3).

Chemical Structure

Cilostamide
Cilostamide
CAS#68550-75-4

Theoretical Analysis

MedKoo Cat#: 563582

Name: Cilostamide

CAS#: 68550-75-4

Chemical Formula: C20H26N2O3

Exact Mass: 342.1943

Molecular Weight: 342.43

Elemental Analysis: C, 70.15; H, 7.65; N, 8.18; O, 14.02

Price and Availability

Size Price Availability Quantity
5mg USD 300.00 2 Weeks
10mg USD 500.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Cilostamide; OPC 3689; OPC-3689; OPC3689;
IUPAC/Chemical Name
N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
InChi Key
UIAYVIIHMORPSJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
SMILES Code
O=C(N(C1CCCCC1)C)CCCOC2=CC3=C(NC(C=C3)=O)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 342.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Takeuchi K, Kita K, Hayashi S, Aihara E. Regulatory mechanism of duodenal bicarbonate secretion: Roles of endogenous prostaglandins and nitric oxide. Pharmacol Ther. 2011 Apr;130(1):59-70. doi: 10.1016/j.pharmthera.2010.12.006. Epub 2010 Dec 24. Review. PubMed PMID: 21185865. 2: Takeuchi K, Koyama M, Hayashi S, Aihara E. Prostaglandin EP receptor subtypes involved in regulating HCO(3)(-) secretion from gastroduodenal mucosa. Curr Pharm Des. 2010;16(10):1241-51. Review. PubMed PMID: 20166995. 3: Nishi T, Kimura Y, Nakagawa K. [Research and development of cilostazol: an antiplatelet agent]. Yakugaku Zasshi. 2000 Dec;120(12):1247-60. Review. Japanese. PubMed PMID: 11193377. 4: Valtin H, Coffey AK, O'Sullivan DJ, Homma S, Dousa TP. Causes of the urinary concentrating defect in mice with nephrogenic diabetes insipidus. Physiol Bohemoslov. 1990;39(1):103-11. Review. PubMed PMID: 2165265.