MedKoo Cat#: 599006 | Name: Litebamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Litebamine is a phenanthrene alkaloid from the wood of Litsea cubeba that inhibits rat smooth muscle cell adhesion and migration on collagen.

Chemical Structure

Litebamine
CAS#137031-56-2

Theoretical Analysis

MedKoo Cat#: 599006

Name: Litebamine

CAS#: 137031-56-2

Chemical Formula: C20H21NO4

Exact Mass: 339.1471

Molecular Weight: 339.39

Elemental Analysis: C, 70.78; H, 6.24; N, 4.13; O, 18.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Litebamine;
IUPAC/Chemical Name
9,11-dimethoxy-2-methyl-1,2,3,4-tetrahydronaphtho[2,1-f]isoquinoline-8,12-diol
InChi Key
QOWFEPGZJDCIKG-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H21NO4/c1-21-7-6-12-13-5-4-11-8-16(22)17(24-2)9-14(11)18(13)20(25-3)19(23)15(12)10-21/h4-5,8-9,22-23H,6-7,10H2,1-3H3
SMILES Code
Oc1c(CN(C)CC2)c2c(c3c1OC)ccc4c3cc(OC)c(O)c4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Teng CM, Hsueh CM, Chang YL, Ko FN, Lee SS, Liu KC. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol. 1997 Jul;49(7):706-11. PubMed PMID: 9255715. 2: Huang CH, Huang WJ, Wang SJ, Wu PH, Wu WB. Litebamine, a phenanthrene alkaloid from the wood of Litsea cubeba, inhibits rat smooth muscle cell adhesion and migration on collagen. Eur J Pharmacol. 2008 Oct 31;596(1-3):25-31. doi: 10.1016/j.ejphar.2008.08.013. Epub 2008 Aug 26. PubMed PMID: 18773889. 3: Chiou CM, Kang JJ, Lee SS. Litebamine N-homologues: preparation and anti-acetylcholinesterase activity. J Nat Prod. 1998 Jan;61(1):46-50. PubMed PMID: 9461651. 4: Wang YS, Wen ZQ, Li BT, Zhang HB, Yang JH. Ethnobotany, phytochemistry, and pharmacology of the genus Litsea: An update. J Ethnopharmacol. 2016 Apr 2;181:66-107. doi: 10.1016/j.jep.2016.01.032. Epub 2016 Jan 23. Review. PubMed PMID: 26812679.