Litalgin | CAS#80186-93-2 | analgesic

MedKoo Cat#: 599004 | Name: Litalgin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Litalgin is a combination of pitofenon, metamizole & dimethylaminoethylbenzilate (benzacine).

Chemical Structure

Litalgin

CAS#80186-93-2

Theoretical Analysis

MedKoo Cat#: 599004

Name: Litalgin

CAS#: 80186-93-2

Chemical Formula: C53H64Cl2N5NaO11S

Exact Mass:

Molecular Weight: 1073.06

Elemental Analysis: C, 59.32; H, 6.01; Cl, 6.61; N, 6.53; Na, 2.14; O, 16.40; S, 2.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Litalgin;

IUPAC/Chemical Name

Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(dimethylamino)ethyl ester, hydrochloride, mixt. with methyl 2-(4-(2-(1-piperidinyl)ethoxy)benzoyl)benzoate hydrochloride and sodium ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)methanesulfonate

InChi Key

PHGXEEJLYUGZLR-UHFFFAOYSA-M

InChi Code

InChI=1S/C22H25NO4.C18H21NO3.C13H17N3O4S.2ClH.Na/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23;1-19(2)13-14-22-17(20)18(21,15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;;/h3-4,7-12H,2,5-6,13-16H2,1H3;3-12,21H,13-14H2,1-2H3;4-8H,9H2,1-3H3,(H,18,19,20);2*1H;/q;;;;;+1/p-1

SMILES Code

O=C(c1ccc(OCCN2CCCCC2)cc1)c3ccccc3C(OC)=O.O=S(CN(c4c(C)n(C)n(c5ccccc5)c4=O)C)([O-])=O.O=C(OCCN(C)C)C(c6ccccc6)(O)c7ccccc7.Cl.[Na+].Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,073.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kanto J, Katevuo K. The effect of drugs with different mechanisms of action on the contraction of the human gallbladder. Int J Clin Pharmacol Ther Toxicol. 1981 Jul;19(7):303-9. Review. PubMed PMID: 7021433. 2: Kanto J, Katevuo K, Mäkelä M. The effect of intravenously administered Palerol and Litalgin on the contraction of the human gallbladder. Int J Clin Pharmacol Ther Toxicol. 1981 May;19(5):206-8. PubMed PMID: 7251235. 3: Tigerstedt I, Leander P, Tammisto T. Postoperative analgesics for superficial surgery. Comparison of four analgesics. Acta Anaesthesiol Scand. 1981 Dec;25(6):543-7. PubMed PMID: 6810642. 4: Niinikoski J, Nelimarkka O, Pekkola P. Intravenous indomethacin in biliary pain. A clinical investigation with metamizole as the control. Ann Chir Gynaecol. 1984;73(2):69-72. PubMed PMID: 6465821. 5: Kalso E, Perttunen K, Kaasinen S. Pain after thoracic surgery. Acta Anaesthesiol Scand. 1992 Jan;36(1):96-100. PubMed PMID: 1539485. 6: Jalovaara P, Kiviniemi H, Ståhlberg M. Comparison of diflunisal and dextropropoxyphene napsylate in the treatment of post-operative pain. Ann Chir Gynaecol. 1985;74(5):228-32. PubMed PMID: 2867731. 7: Rosenberg PH, Heino A, Scheinin B. Comparison of intramuscular analgesia, intercostal block, epidural morphine and on-demand-i.v.-fentanyl in the control of pain after upper abdominal surgery. Acta Anaesthesiol Scand. 1984 Dec;28(6):603-7. PubMed PMID: 6524275.