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MedKoo Cat#: 563568 | Name: AMG21629

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AMG21629 is a potent and selective TRPV1 antagonist.

Chemical Structure

AMG21629
AMG21629
CAS#939040-79-6

Theoretical Analysis

MedKoo Cat#: 563568

Name: AMG21629

CAS#: 939040-79-6

Chemical Formula: C22H19F3N6O3

Exact Mass: 472.1471

Molecular Weight: 472.42

Elemental Analysis: C, 55.93; H, 4.05; F, 12.06; N, 17.79; O, 10.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AMG21629; AMG-21629; AMG 21629;
IUPAC/Chemical Name
3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone
InChi Key
TUMYQRZCVIQKOQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H19F3N6O3/c1-33-10-9-27-21-29-15(12-5-7-13(8-6-12)22(23,24)25)11-17(30-21)34-16-4-2-3-14-18(16)31-19(26)20(32)28-14/h2-8,11H,9-10H2,1H3,(H2,26,31)(H,28,32)(H,27,29,30)
SMILES Code
O=C1NC2=C(C(OC3=NC(NCCOC)=NC(C4=CC=C(C(F)(F)F)C=C4)=C3)=CC=C2)N=C1N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 472.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zareie P, Sadegh M, Palizvan MR, Moradi-Chameh H. Anticonvulsive effects of endocannabinoids; an investigation to determine the role of regulatory components of endocannabinoid metabolism in the Pentylenetetrazol induced tonic- clonic seizures. Metab Brain Dis. 2018 Jun;33(3):939-948. doi: 10.1007/s11011-018-0195-5. Epub 2018 Mar 4. PubMed PMID: 29504066.