IUPAC/Chemical Name
(S)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol
InChi Key
YXVXMURDCBMPRH-AWEZNQCLSA-N
InChi Code
InChI=1S/C18H19NO2/c1-19-8-7-12-10-15(21-2)18(20)17-13-6-4-3-5-11(13)9-14(19)16(12)17/h3-6,10,14,20H,7-9H2,1-2H3/t14-/m0/s1
SMILES Code
OC1=C(OC)C=C2CCN(C)[C@@]3([H])CC4=CC=CC=C4C1=C23
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
281.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kang YF, Liu CM, Kao CL, Chen CY. Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera. Molecules. 2014 Apr 3;19(4):4234-45. doi: 10.3390/molecules19044234. PubMed PMID: 24705566.
2: Shoji N, Umeyama A, Saito N, Iuchi A, Takemoto T, Kajiwara A, Ohizumi Y. Asimilobine and lirinidine, serotonergic receptor antagonists, from Nelumbo nucifera. J Nat Prod. 1987 Jul-Aug;50(4):773-4. PubMed PMID: 3430176.
3: Nakamura S, Nakashima S, Tanabe G, Oda Y, Yokota N, Fujimoto K, Matsumoto T, Sakuma R, Ohta T, Ogawa K, Nishida S, Miki H, Matsuda H, Muraoka O, Yoshikawa M. Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells. Bioorg Med Chem. 2013 Feb 1;21(3):779-87. doi: 10.1016/j.bmc.2012.11.038. Epub 2012 Dec 5. PubMed PMID: 23270663.
4: Phillipson JD, Thomas OO, Gray AI, Sariyar G. Alkaloids from Papaver armeniacum, P. fugax and P. tauricola. Planta Med. 1981 Feb;41(2):105-18. PubMed PMID: 17401828.
5: Chang FR, Wei JL, Teng CM, Wu YC. Two new 7-dehydroaporphine alkaloids and antiplatelet action aporphines from the leaves of Annona purpurea. Phytochemistry. 1998 Dec;49(7):2015-8. PubMed PMID: 9883592.
