Pikamilone Sodium | CAS#62936-56-5 | GABA prodrug

MedKoo Cat#: 563558 | Name: Pikamilone Sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pikamilone Sodium is a prodrug of GABA used for treatment of neurogenic bladder in spinal and benign prostatic hyperplasia.

Chemical Structure

Pikamilone Sodium

CAS#62936-56-5

Theoretical Analysis

MedKoo Cat#: 563558

Name: Pikamilone Sodium

CAS#: 62936-56-5

Chemical Formula: C10H11N2NaO3

Exact Mass: 230.0667

Molecular Weight: 230.19

Elemental Analysis: C, 52.18; H, 4.82; N, 12.17; Na, 9.99; O, 20.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Pikamilone Sodium; Pikamilone Na; GABA-NG; Nicotinoyl-GABA sodium salt; GABA NG; GABANG;

IUPAC/Chemical Name

Sodium 4-(pyridine-3-carbonylamino)butanoate

InChi Key

DGWZSECHAXUHPD-UHFFFAOYSA-M

InChi Code

InChI=1S/C10H12N2O3.Na/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8;/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14);/q;+1/p-1

SMILES Code

O=C([O-])CCCNC(C1=CC=CN=C1)=O.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 230.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Karaev AL, Kovler MA, Avakumov VM, Kopelevich VM, Bulanova LN. [Antihypoxic properties of GABA-containing vitamin derivatives]. Farmakol Toksikol. 1989 Jan-Feb;52(1):56-8. Russian. PubMed PMID: 2707423. 2: Mirzoian RS, Gan'shina TS. [The new cerebrovascular preparation pikamilon]. Farmakol Toksikol. 1989 Jan-Feb;52(1):23-6. Russian. PubMed PMID: 2707413. 3: Voronina TA, Garibova TL, Khromova IV, Tilekeeva UM. [Dissociation of the anti-amnesic and antihypoxic effects of nootropic and antihypoxic preparations]. Farmakol Toksikol. 1987 May-Jun;50(3):21-4. Russian. PubMed PMID: 3609269. 4: Burov IuV, Orekhov SN, Iukhananov RIu, Vedernikova NN. [Role of benzodiazepine receptors in realizing the anxiolytic effect of compounds on intact rats and on animals with a physical dependence ethanol]. Biull Eksp Biol Med. 1986 Feb;101(2):170-2. Russian. PubMed PMID: 2868765.