Glyceryl monolinoleate, also known as mono-linolein or glyceryl 9,12-octadecadienoate, is a monoacylglycerol derivative of linoleic acid. It has been studied primarily for its bioactivity in dermatological and antimicrobial contexts. Glyceryl monolinoleate exhibits antimicrobial activity against Gram-positive bacteria such as Staphylococcus aureus, with minimum inhibitory concentrations (MICs) reported in the range of 64–128 µg/mL. It also shows moderate antifungal activity. In skin-related studies, it enhances percutaneous drug absorption and improves skin hydration by acting as a penetration enhancer and emollient.
MedKoo Cat#: 598934
Name: Glyceryl monolinoleate
CAS#: 26545-74-4
Chemical Formula: C21H38O4
Exact Mass: 0.0000
Molecular Weight: 354.53
Elemental Analysis: C, 71.14; H, 10.80; O, 18.05
The following data is based on the product molecular weight 354.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
